Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FOS | P01100 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17540838 | 0.84 | KDM4E (0.46) | KDM4EATMCSNK2A1TAAR1TSHR | |
| SCHEMBL12961032 | 0.83 | ATM (0.42) | KDM4EATMTAAR1TSHRMAPK1 | |
| SCHEMBL22838628 | 0.83 | TTR (0.42) | TSHRFOSTTRJUNNR3C1 | |
| SCHEMBL25687627 | 0.80 | ALDH1A1 (0.61) | KDM4ETSHRALDH1A1LMNA | |
| SCHEMBL19263401 | 0.77 | CSNK2A1 (0.38) | CSNK2A1TSHRALDH1A1 | |
| SCHEMBL10175139 | 0.77 | HDAC4 (0.43) | TSHRALDH1A1LMNA | |
| SCHEMBL2632721 | 0.77 | ACHE (0.50) | KDM4EMAPK1ALDH1A1 | |
| SCHEMBL12606793 | 0.77 | CA12 (0.50) | ALDH1A1HTR2ACA2 | |
| SCHEMBL11437277 | 0.77 | CA12 (0.50) | ALDH1A1HTR2ACA2 | |
| SCHEMBL10172021 | 0.77 | CA12 (0.50) | ALDH1A1HTR2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670157-B2 | Benzylamine derivatives | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2017-06-06 | — | — | US | disclosed |