Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1296194 | 1.00 | ABCB1 (0.42) | ABCB1ALDH1A1MAPK1L3MBTL1ATM | |
| SCHEMBL16245288 | 0.82 | SLC15A1 (0.44) | ABCB1ALDH1A1MAPK1L3MBTL1ATM | |
| SCHEMBL21383918 | 0.82 | HTT (0.46) | ABCB1L3MBTL1ATMHTTSMN1; SMN2 | |
| SCHEMBL12567292 | 0.81 | KCNA5 (0.32) | ALDH1A1 | |
| SCHEMBL18196801 | 0.80 | ALDH1A1 (0.42) | ABCB1ALDH1A1MAPK1L3MBTL1ATM | |
| SCHEMBL1295495 | 0.79 | TSHR (0.30) | — | |
| SCHEMBL1295490 | 0.79 | TSHR (0.30) | — | |
| SCHEMBL8301377 | 0.79 | ABCB1 (0.45) | ABCB1ALDH1A1MAPK1L3MBTL1ATM | |
| SCHEMBL21383920 | 0.78 | HTT (0.44) | ABCB1L3MBTL1ATMHTTSMN1; SMN2 | |
| SCHEMBL15653580 | 0.77 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269962-A1 | PROCESS FOR PREPARING STATINS | DIPHARMA FRANCIS S.R.L. (IT) | 2011-11-03 | — | — | US | disclosed |
| EP-2383260-A2 | Process for the preparation of statins | Dipharma Francis S.r.l. (IT) | 2011-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269962-A1 | PROCESS FOR PREPARING STATINS | HMGCR, CYP51A1, PCSK9 | ABCB1 1240/4885ALDH1A1 3699/4885MAPK1 2771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.