Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18196801 | 0.85 | ALDH1A1 (0.42) | SLC15A1ALDH1A1MAPK1L3MBTL1ATM | |
| SCHEMBL1296191 | 0.82 | ABCB1 (0.42) | SLC15A1ALDH1A1MAPK1L3MBTL1ATM | |
| SCHEMBL1296194 | 0.82 | ABCB1 (0.42) | SLC15A1ALDH1A1MAPK1L3MBTL1ATM | |
| SCHEMBL22181023 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL20966567 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL16614401 | 0.81 | ALDH1A1 (0.39) | SLC15A1ALDH1A1MAPK1L3MBTL1ATM | |
| SCHEMBL16614382 | 0.81 | ALDH1A1 (0.39) | SLC15A1ALDH1A1MAPK1L3MBTL1ATM | |
| SCHEMBL8301377 | 0.79 | ABCB1 (0.45) | SLC15A1ALDH1A1MAPK1L3MBTL1ATM | |
| SCHEMBL20966572 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL5400528 | 0.78 | ALDH1A1 (0.44) | SLC15A1ALDH1A1MAPK1L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273333-B2 | Process for the preparation of intermediates of HMG-CoA reductase inhibitors | MYLAN LABORATORIES LTD (IN) | 2016-03-01 | — | — | US | disclosed |
| US-20140349350-A1 | Novel Process for the Preparation of Intermediates of HMG-CoA Reductase Inhibitors | TIANISH LABORATORIES PRIVATE LIMITED (IN) | 2014-11-27 | — | — | US | disclosed |