Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | RRM1 | P23921 | 1/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12964824 | 1.00 | NOD1 (0.53) | NOD1DPP7DPP4DPP8DPP9 | |
| SCHEMBL18264750 | 0.92 | DPP4 (0.50) | NOD1DPP7DPP4DPP8DPP9 | |
| SCHEMBL4164602 | 0.87 | DPP7 (0.67) | NOD1DPP7DPP4DPP8DPP9 | |
| SCHEMBL10046565 | 0.87 | DPP7 (0.67) | NOD1DPP7DPP4DPP8DPP9 | |
| SCHEMBL11982810 | 0.86 | NOD1 (0.54) | NOD1DPP7DPP4DPP8DPP9 | |
| SCHEMBL31593390 | 0.86 | DPP4 (0.44) | NOD1DPP4DPP8DPP9 | |
| SCHEMBL31674332 | 0.84 | NOD1 (0.52) | NOD1DPP7DPP4DPP8DPP9 | |
| SCHEMBL18110511 | 0.84 | NOD1 (0.64) | NOD1GLP1R | |
| SCHEMBL19685304 | 0.84 | NOD1 (0.52) | NOD1DPP7RRM1GNAI3GNAO1 | |
| SCHEMBL12964934 | 0.83 | SIRT6 (0.54) | SIRT6SIRT1PLA2G2CGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130866-A1 | NOVEL GLUCAGON ANALOGUES | NOVO NORDISK A/S (DK) | 2012-10-04 | — | — | WO | disclosed |