Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47287 | 1.00 | MAPT (0.48) | MAPTNPC1RAB9ACYP1A2GAA | |
| SCHEMBL12966537 | 0.85 | CYP1A2 (0.46) | MAPTNPC1RAB9ACYP1A2GAA | |
| SCHEMBL12966650 | 0.85 | MAPT (0.60) | MAPTNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL12966551 | 0.84 | LMNA (0.48) | MAPTNPC1RAB9ACYP1A2GAA | |
| SCHEMBL41667 | 0.83 | MAPT (0.43) | MAPTNPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL41666 | 0.83 | MAPT (0.43) | MAPTNPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL12966662 | 0.83 | MAPT (0.51) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12966543 | 0.83 | NPC1 (0.42) | MAPTNPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL12966544 | 0.82 | KMT2A (0.46) | MAPTNPC1RAB9ACYP1A2GAA | |
| SCHEMBL38787 | 0.80 | MAPT (0.55) | MAPTNPC1RAB9AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130850-A1 | TISSUE TARGETING BY MEANS OF ONCOCIDAL BRIDGED DIPHENYL DERIVATIVES FOR THE SELECTIVE TREATMENT OF SEXUAL ORGAN TUMORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-10-04 | — | — | WO | disclosed |