Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12966897 | 0.86 | MAPT (0.53) | GAANPC1MAPTRAB9ATDP1 | |
| SCHEMBL47287 | 0.85 | MAPT (0.48) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL12966626 | 0.85 | MAPT (0.48) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL12966551 | 0.83 | LMNA (0.48) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL17710847 | 0.78 | CYP1A2 (0.67) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL17710899 | 0.78 | CYP1A2 (0.67) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL12966540 | 0.76 | LTA4H (0.60) | NPC1MAPTRAB9A | |
| SCHEMBL12966535 | 0.76 | PPARA (0.58) | PPARGPPARA | |
| SCHEMBL2475726 | 0.76 | LMNA (0.50) | PKMNPC1MAPTRAB9ATDP1 | |
| SCHEMBL10967275 | 0.76 | EPHX2 (0.64) | CYP1A2GAACYP2C9PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130850-A1 | TISSUE TARGETING BY MEANS OF ONCOCIDAL BRIDGED DIPHENYL DERIVATIVES FOR THE SELECTIVE TREATMENT OF SEXUAL ORGAN TUMORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-10-04 | — | — | WO | disclosed |