Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | ACR | P10323 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12966897 | 0.88 | MAPT (0.53) | MAPTNPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL12966900 | 0.87 | MAPT (0.59) | MAPTNPC1RAB9ALMNAKMT2A | |
| SCHEMBL12966652 | 0.86 | MAPT (0.51) | MAPTNPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL12966626 | 0.85 | MAPT (0.48) | MAPTNPC1RAB9ALMNAKMT2A | |
| SCHEMBL47287 | 0.85 | MAPT (0.48) | MAPTNPC1RAB9ALMNAKMT2A | |
| SCHEMBL12966898 | 0.84 | MAPT (0.53) | MAPTNPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL12966653 | 0.84 | MAPT (0.55) | MAPTNPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL12967067 | 0.81 | NPC1 (0.52) | MAPTNPC1RAB9AALDH1A1ALDH2 | |
| SCHEMBL47175 | 0.80 | MAPT (0.62) | MAPTNPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL41666 | 0.79 | MAPT (0.43) | MAPTNPC1RAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130850-A1 | TISSUE TARGETING BY MEANS OF ONCOCIDAL BRIDGED DIPHENYL DERIVATIVES FOR THE SELECTIVE TREATMENT OF SEXUAL ORGAN TUMORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-10-04 | — | — | WO | disclosed |