Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12966692 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL7915995 | 0.85 | KDM4E (0.52) | SMN1; SMN2KDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL12966730 | 0.84 | KDM4E (0.51) | SMN1; SMN2KDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL12966731 | 0.83 | ALDH1A1 (0.58) | SMN1; SMN2KDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL12966750 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL7905684 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL7906084 | 0.78 | GAA (0.54) | SMN1; SMN2ALDH1A1GAARECQLMAPT | |
| SCHEMBL7713619 | 0.76 | PLA2G4B (0.56) | ALDH1A1LMNAGAAHTTRECQL | |
| SCHEMBL2633187 | 0.76 | CYP4F2 (0.64) | SMN1; SMN2KDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL7153441 | 0.75 | POLB (0.56) | SMN1; SMN2KDM4ECYP1A2CYP2D6PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120252741-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | BIOMARIN PHARMACEUTICAL INC. (US) | 2012-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252741-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | ASNS, DNPEP, ALG8 | SMN1; SMN2 3534/4885KDM4E 701/4885CYP1A2 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.