Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760020 | 0.81 | PARP14 (0.54) | MAPTMAPK1NPSR1KIF11PARP14 | |
| SCHEMBL7656635 | 0.77 | KIF11 (0.46) | MAPTRAB9AKIF11PARP14KDM4E | |
| SCHEMBL2519316 | 0.75 | KIF11 (0.55) | MAPTMAPK1NPSR1RAB9AKIF11 | |
| SCHEMBL29836254 | 0.75 | KIF11 (0.55) | MAPTMAPK1NPSR1RAB9AKIF11 | |
| Ammonia Solution, Strong SCHEMBL28526125 | 0.73 | KIF11 (0.53) | MAPTMAPK1NPSR1RAB9AKIF11 | |
| SCHEMBL30658552 | 0.73 | KIF11 (0.53) | MAPTMAPK1NPSR1RAB9AKIF11 | |
| SCHEMBL27921829 | 0.72 | PARP14 (0.54) | MAPTMAPK1NPSR1KIF11PARP14 | |
| SCHEMBL3189571 | 0.72 | KIF11 (0.59) | MAPTMAPK1NPSR1NQO2KIF11 | |
| SCHEMBL3840020 | 0.71 | ALDH1A1 (0.43) | MAPTMAPK1NPSR1RAB9AKIF11 | |
| SCHEMBL3197265 | 0.71 | RAB9A (0.53) | MAPTMAPK1NPSR1RAB9AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012135133-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2012-10-04 | — | — | WO | disclosed |