Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28500585 | 0.81 | MAPT (0.33) | MAPTTDP1L3MBTL1KDM4EUSP2 | |
| SCHEMBL18602231 | 0.78 | NPC1 (0.47) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL14420497 | 0.77 | ALDH1A1 (0.45) | MAPTTDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL13103327 | 0.77 | GAA (0.42) | MAPTTDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18602458 | 0.75 | ALDH1A1 (0.33) | L3MBTL1KDM4EALDH1A1RECQLRAB9A | |
| SCHEMBL10644473 | 0.75 | CNR2 (0.38) | MAPTL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL19390301 | 0.75 | ACHE (0.33) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13488450 | 0.74 | IFNAR1 (0.33) | — | |
| SCHEMBL28259951 | 0.74 | APP (0.32) | — | |
| SCHEMBL25079074 | 0.71 | DRD2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012135636-A1 | LANTIBIOTIC NAI-802, PHARMACEUTICALLY ACCEPTABLE SALTS, COMPOSITIONS, AND USES THEREOF | SENTINELLA PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |