Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.76 |
| ▸ | PGR | P06401 | 5/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | TNF | P01375 | 1/20 | 0.76 |
| ▸ | IL6 | P05231 | 1/20 | 0.76 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.76 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.76 |
| ▸ | AR | P10275 | 1/20 | 0.76 |
| ▸ | GLUL | P15104 | 1/20 | 0.76 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.76 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.59 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685803 | 1.00 | NR3C1 (0.76) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| SCHEMBL15796471 | 1.00 | NR3C1 (0.76) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| SCHEMBL12738238 | 1.00 | NR3C1 (0.76) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| SCHEMBL5098329 | 1.00 | NR3C1 (0.76) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| SCHEMBL13379819 | 1.00 | NR3C1 (0.76) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| SCHEMBL10333932 | 0.90 | NR3C1 (0.73) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| SCHEMBL10333933 | 0.90 | NR3C1 (0.73) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| SCHEMBL5098424 | 0.90 | PGR (0.77) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| SCHEMBL1685716 | 0.90 | PGR (0.77) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| SCHEMBL13929909 | 0.89 | NR3C1 (0.66) | NR3C1PGRHIF1AHSD17B10ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140171645-A1 | ELECTROPHILIC ALKYLATING REAGENTS, THEIR PREPARATION AND USE | HOVIONE INTER LTD. (CH) | 2014-06-19 | — | — | US | disclosed |
| US-20140171645-A1 | ELECTROPHILIC ALKYLATING REAGENTS, THEIR PREPARATION AND USE | HOVIONE INTER LTD. (CH) | 2014-06-19 | — | — | US | disclosed |
| WO-2012131286-A1 | ELECTROPHILIC ALKYLATING REAGENTS, THEIR PREPARATION AND USE | HOVIONE INTER. LTD (CH) | 2012-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140171645-A1 | ELECTROPHILIC ALKYLATING REAGENTS, THEIR PREPARATION AND USE | MGMT, MCL1, TOP2B | NR3C1 1595/4885PGR 3045/4885HIF1A 2680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.