Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 4/20 | 0.40 |
| ▸ | DDO | Q99489 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12970315 | 0.86 | GRIN2D (0.47) | BRD4DAODDOGRIN2DGRIN3B | |
| SCHEMBL22198970 | 0.84 | HRH4 (0.45) | BRD4HRH4DAODDOGRIN2D | |
| SCHEMBL19435615 | 0.84 | BRD4 (0.40) | BRD4DAODDOGRIN2DGRIN3B | |
| SCHEMBL12970395 | 0.78 | DAO (0.65) | BRD4HRH4DAODDOHSD17B10 | |
| SCHEMBL3420670 | 0.77 | DAO (0.64) | HRH4DAODDO | |
| SCHEMBL1757449 | 0.75 | HRH4 (0.41) | HRH4DAOALDH1A1 | |
| SCHEMBL1367893 | 0.74 | HRH4 (0.42) | HRH4DAODDOGRIN2DGRIN3B | |
| SCHEMBL26617488 | 0.72 | ALDH1A1 (0.56) | ALDH1A1LMNA | |
| SCHEMBL22198962 | 0.72 | TNF (0.43) | BRD4DAODDOGRIN2DGRIN3B | |
| SCHEMBL24107972 | 0.70 | CYP1A1 (0.44) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012133607-A1 | PYRAZOLE COMPOUND | アステラス製薬株式会社 (JP) | 2012-10-04 | — | — | WO | disclosed |