SCHEMBL3420670

SCHEMBL3420670

O=c1[nH]c2c(F)cc(F)cc2cc1O

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DAO P14920 17/20 0.64
DDO Q99489 6/20 0.64
HRH4 Q9H3N8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3361624 0.84 DAO (0.58) DAODDOHRH4
SCHEMBL3361286 0.81 DAO (0.60) DAODDO
SCHEMBL3422795 0.79 DAO (0.62) DAODDO
SCHEMBL3362300 0.78 DAO (1.00) DAODDOHRH4
SCHEMBL1367893 0.78 HRH4 (0.42) DAODDOHRH4
SCHEMBL12970080 0.77 BRD4 (0.43) DAODDOHRH4
SCHEMBL16767846 0.72 DAO (1.00) DAODDO
SCHEMBL3363037 0.72 DAO (0.61) DAODDO
SCHEMBL3363264 0.72 DAO (0.61) DAODDO
SCHEMBL3362656 0.71 DAO (0.61) DAODDOHRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010058314-A1 HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF PFIZER INC. (US) 2010-05-27 WO disclosed