Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 2/20 | 0.47 |
| ▸ | EP300 | Q09472 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.39 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12970125 | 0.85 | MAP2K4 (0.48) | MAP2K4EP300FYNHDAC1MALT1 | |
| SCHEMBL24602339 | 0.82 | RPS6KA3 (0.45) | MAPK1DHODHRPS6KA3CYP11B1CYP11B2 | |
| SCHEMBL12970557 | 0.82 | MAP2K4 (0.46) | MAP2K4EP300FYNHDAC1MALT1 | |
| SCHEMBL12970528 | 0.80 | FYN (0.48) | MAP2K4EP300FYNPOLB | |
| SCHEMBL31665020 | 0.80 | KIF11 (0.49) | MAP2K4EP300KIF11FYNPOLB | |
| SCHEMBL13562426 | 0.79 | FYN (0.46) | MAP2K4EP300KIF11FYNMKNK1 | |
| SCHEMBL17249597 | 0.74 | MAP2K4 (0.46) | MAP2K4KIF11HDAC1MAPK1MAPKAPK2 | |
| SCHEMBL29502570 | 0.73 | AGBL2 (0.43) | MAP2K4EP300KIF11FYNPOLB | |
| SCHEMBL12970086 | 0.73 | MKNK1 (0.43) | MAP2K4FYNMKNK1MKNK2 | |
| SCHEMBL31521744 | 0.72 | MKNK1 (0.47) | MAP2K4KIF11FYNDHODHMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012133607-A1 | PYRAZOLE COMPOUND | アステラス製薬株式会社 (JP) | 2012-10-04 | — | — | WO | disclosed |