Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529366 | 0.87 | L3MBTL1 (0.61) | POLBTLR8L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL10641295 | 0.87 | L3MBTL1 (0.61) | POLBTLR8L3MBTL1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9847504 | 0.86 | L3MBTL1 (0.60) | POLBMEN1KMT2ATLR8L3MBTL1 | |
| SCHEMBL12970102 | 0.84 | TLR8 (0.49) | POLBMEN1KMT2ATLR8L3MBTL1 | |
| SCHEMBL9590284 | 0.83 | TLR8 (0.67) | POLBMEN1KMT2ATLR8L3MBTL1 | |
| SCHEMBL9590301 | 0.81 | TLR8 (0.56) | POLBMEN1KMT2ATLR8L3MBTL1 | |
| SCHEMBL12970154 | 0.79 | PDE10A (0.74) | MEN1KMT2AALDH1A1KDM4EAR | |
| SCHEMBL12402675 | 0.76 | KDM4E (0.63) | POLBMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL4260071 | 0.76 | PDGFRB (0.55) | POLBMEN1KMT2ATLR8L3MBTL1 | |
| SCHEMBL29207060 | 0.75 | KDM4E (0.60) | TLR8L3MBTL1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012133607-A1 | PYRAZOLE COMPOUND | アステラス製薬株式会社 (JP) | 2012-10-04 | — | — | WO | disclosed |