Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.61 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.61 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | WHR1 | P49842 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10641295 | 1.00 | L3MBTL1 (0.61) | L3MBTL1PDE10ATLR8ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9847504 | 0.95 | L3MBTL1 (0.60) | L3MBTL1PDE10ATLR8ALDH1A1KDM4E | |
| SCHEMBL9590284 | 0.89 | TLR8 (0.67) | L3MBTL1PDE10ATLR8ALDH1A1KDM4E | |
| SCHEMBL12970331 | 0.87 | POLB (0.55) | L3MBTL1PDE10ATLR8ALDH1A1KDM4E | |
| SCHEMBL29366598 | 0.85 | PDE10A (0.59) | L3MBTL1PDE10ATLR8ALDH1A1KDM4E | |
| SCHEMBL4260071 | 0.84 | PDGFRB (0.55) | L3MBTL1PDE10ATLR8ALDH1A1GAA | |
| SCHEMBL29207074 | 0.84 | KDM4E (0.62) | L3MBTL1PDE10ATLR8ALDH1A1KDM4E | |
| SCHEMBL30486859 | 0.84 | L3MBTL1 (0.59) | L3MBTL1PDE10ATLR8ALDH1A1KDM4E | |
| SCHEMBL29207032 | 0.84 | L3MBTL1 (0.59) | L3MBTL1PDE10ATLR8ALDH1A1KDM4E | |
| SCHEMBL12970102 | 0.83 | TLR8 (0.49) | L3MBTL1PDE10ATLR8ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250145599-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MRJA THERAPEUTICS, INC. | 2025-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145599-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | IGF1R, IGFBP1, IGFBP2 | L3MBTL1 4482/4885PDE10A 828/4885TLR8 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.