SCHEMBL12972013

SCHEMBL12972013

CCC(C)(O)C1CC2CCC1C2

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.35
EPHX2 P34913 1/20 0.33
HSD11B1 P28845 2/20 0.33
MAPT P10636 2/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32
GFER P55789 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
POLB P06746 1/20 0.32
HTT P42858 1/20 0.31
BRS3 P32247 1/20 0.30
PANK3 Q9H999 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5196815 0.82 CNR2 (0.32) CYP19A1EPHX2
SCHEMBL12971937 0.82 CYP19A1 (0.36) CYP19A1EPHX2HSD11B1MAPTNPC1
SCHEMBL27433178 0.79 EPHX2 (0.32) CYP19A1EPHX2HSD11B1MAPTNPC1
SCHEMBL5194757 0.79 CYP19A1 (0.38) CYP19A1EPHX2HSD11B1MAPTL3MBTL1
SCHEMBL5194124 0.79 CYP19A1 (0.38) CYP19A1EPHX2HSD11B1MAPTNPC1
SCHEMBL9934752 0.79 CYP19A1 (0.38) CYP19A1EPHX2HSD11B1MAPTL3MBTL1
SCHEMBL32688730 0.78 POLB (0.35) CYP19A1EPHX2HSD11B1MAPTNPC1
SCHEMBL9934219 0.77 CYP19A1 (0.33) CYP19A1EPHX2HSD11B1MAPTNPC1
SCHEMBL14213229 0.77 EPHX2 (0.36) CYP19A1EPHX2HSD11B1MAPTNPC1
SCHEMBL6853761 0.75 CYP19A1 (0.31) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8791288-B2 Acid-labile ester monomer having spirocyclic structure, polymer, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-07-29 US disclosed
US-8791288-B2 Acid-labile ester monomer having spirocyclic structure, polymer, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-07-29 US disclosed
US-20100304295-A1 ACID-LABILE ESTER MONOMER HAVING SPIROCYCLIC STRUCTURE, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-12-02 US disclosed
US-20100304295-A1 ACID-LABILE ESTER MONOMER HAVING SPIROCYCLIC STRUCTURE, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100304295-A1 ACID-LABILE ESTER MONOMER HAVING SPIROCYCLIC STRUCTURE, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS COASY, DHCR24, HCAR1 CYP19A1 168/4885EPHX2 27/4885HSD11B1 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.