Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348591 | 0.92 | ESR1 (0.59) | ESR1TSHRALDH1A1RECQLNPC1 | |
| SCHEMBL19795495 | 0.88 | ESR1 (0.65) | ESR1TSHRMAPK1ALDH1A1RECQL | |
| SCHEMBL522911 | 0.86 | ESR1 (0.67) | ESR1TSHRMAPK1ALDH1A1LMNA | |
| SCHEMBL522412 | 0.82 | TSHR (0.53) | TSHRMAPK1ALDH1A1RECQLLMNA | |
| SCHEMBL8345769 | 0.81 | ESR1 (0.77) | ESR1TSHRMAPK1ALDH1A1RECQL | |
| SCHEMBL19795492 | 0.79 | ESR1 (0.59) | ESR1TSHRALDH1A1LMNATDP1 | |
| SCHEMBL11004733 | 0.77 | ALDH1A1 (0.58) | ESR1TSHRMAPK1ALDH1A1LMNA | |
| SCHEMBL1719721 | 0.77 | TSHR (0.59) | ESR1TSHRMAPK1ALDH1A1RECQL | |
| SCHEMBL17367633 | 0.77 | ESR1 (0.83) | ESR1TSHRMAPK1ALDH1A1RECQL | |
| SCHEMBL522646 | 0.76 | ESR1 (0.56) | ESR1TSHRMAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7854863-B2 | Functional materials for use in optical systems | BATTELLE MEMORIAL INSTITUTE (US) | 2010-12-21 | — | — | US | disclosed |