SCHEMBL8348591

SCHEMBL8348591

CCCOC(=O)c1c(F)c(F)c(F)c(F)c1C(=O)OCCC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.59
ALDH1A1 P00352 3/20 0.48
LMNA P02545 1/20 0.47
TDP1 Q9NUW8 3/20 0.46
TSHR P16473 2/20 0.46
CHRM1 P11229 1/20 0.46
SLC6A2 P23975 1/20 0.46
KDR P35968 1/20 0.46
MAPT P10636 2/20 0.44
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
RECQL P46063 2/20 0.39
TP53 P04637 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 1/20 0.39
MITF O75030 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19795495 0.96 ESR1 (0.65) ESR1ALDH1A1LMNATDP1TSHR
SCHEMBL522911 0.93 ESR1 (0.67) ESR1ALDH1A1LMNATDP1TSHR
SCHEMBL12972452 0.92 ESR1 (0.53) ESR1ALDH1A1LMNATDP1TSHR
SCHEMBL8345769 0.88 ESR1 (0.77) ESR1ALDH1A1LMNATDP1TSHR
SCHEMBL19795492 0.86 ESR1 (0.59) ESR1ALDH1A1LMNATDP1TSHR
SCHEMBL11004733 0.84 ALDH1A1 (0.58) ESR1ALDH1A1LMNATDP1TSHR
SCHEMBL17367633 0.83 ESR1 (0.83) ESR1ALDH1A1LMNATDP1TSHR
SCHEMBL19795485 0.83 ESR1 (0.51) ESR1ALDH1A1LMNATDP1TSHR
SCHEMBL522646 0.83 ESR1 (0.56) ESR1ALDH1A1LMNATDP1TSHR
SCHEMBL6578769 0.82 SMN1; SMN2 (0.53) ESR1ALDH1A1TDP1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5856557-A Process for producing hexafluorobiphenyl -3,3',4,4'-Tetracarboxylic acid precursors UBE INDUSTRIES, LTD. (JP) 1999-01-05 US claimed
US-5856557-A Process for producing hexafluorobiphenyl -3,3',4,4'-Tetracarboxylic acid precursors UBE INDUSTRIES, LTD. (JP) 1999-01-05 US disclosed