Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25143831 | 0.83 | ACHE (0.70) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL16306480 | 0.78 | CES2 (0.57) | ACHEMEN1MAPTKMT2A | |
| SCHEMBL26227327 | 0.77 | MCL1 (0.45) | ACHEMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL10817081 | 0.77 | ACHE (0.81) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8381680 | 0.77 | ACHE (0.74) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13238330 | 0.77 | ACHE (0.50) | ACHE | |
| SCHEMBL7687507 | 0.76 | ACHE (0.78) | ACHE | |
| SCHEMBL16301543 | 0.76 | ACHE (0.60) | ACHE | |
| SCHEMBL14415956 | 0.75 | FAAH (0.43) | ALDH1A1L3MBTL1 | |
| SCHEMBL21793130 | 0.75 | CES2 (0.58) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7847034-B2 | Adducts and curable compositions using same | LOCTITE (R&D) LIMITED (IE) | 2010-12-07 | — | — | US | disclosed |