Ether

Ether

SCHEMBL129739

CCOCC.OCCCCC(O)CO

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.44
USP2 O75604 2/20 0.38
ALDH1A1 P00352 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.35
PSMD14 O00487 2/20 0.34
PLA2G1B P04054 2/20 0.34
MMP2 P08253 2/20 0.34
ATG4B Q9Y4P1 2/20 0.34
HSP90AA1 P07900 1/20 0.34
RAD52 P43351 1/20 0.34
LMNA P02545 5/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.33
PLA2G2C Q5R387 1/20 0.33
GPR84 Q9NQS5 3/20 0.31
CYP2D6 P10635 2/20 0.31
SPHK1 Q9NYA1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Ethoxyethanol SCHEMBL28224941 0.90 ALDH1A1 (0.54) THRBUSP2ALDH1A1SMN1; SMN2PSMD14
1,6-Hexanediol SCHEMBL18789298 0.86 USP2 (0.45) THRBUSP2ALDH1A1SMN1; SMN2LMNA
Alcohol SCHEMBL4425490 0.86 THRB (0.52) THRBUSP2ALDH1A1SMN1; SMN2PSMD14
Methyl Alcohol SCHEMBL28239246 0.84 THRB (0.55) THRBUSP2ALDH1A1SMN1; SMN2PSMD14
SCHEMBL28179960 0.83
SCHEMBL10902826 0.83 THRB (0.61) THRBUSP2ALDH1A1SMN1; SMN2PSMD14
1,4-Butanediol SCHEMBL7613410 0.83 THRB (0.61) THRBUSP2ALDH1A1SMN1; SMN2PSMD14
SCHEMBL35437 0.83
SCHEMBL4162036 0.83
Butyl Alcohol SCHEMBL28472879 0.82 ALDH1A1 (0.52) THRBUSP2ALDH1A1SMN1; SMN2PSMD14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1079665-C Personal cleansing compositions PROCTER & GAMBLE (US) 2002-02-27 CN claimed
US-5989536-A Personal cleansing compositions containing alkoxylated ether and cationic ammonium salt for deposition of active agent upon the skin THE PROCTER & GAMBLE COMPANY (US) 1999-11-23 US claimed
EP-0714283-B1 PERSONAL CLEANSING COMPOSITIONS PROCTER & GAMBLE (US) 1999-05-12 EP claimed
CN-1130864-A Personal cleansing compositions PROCTER & GAMBLE (US) 1996-09-11 CN claimed
EP-0714283-A1 PERSONAL CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1996-06-05 EP claimed
WO-1995003781-A1 PERSONAL CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1995-02-09 WO claimed
EP-1469813-B1 ADDITIVES AND PRODUCTS INCLUDING OLIGOESTERS CRODA INC (US) 2016-12-21 EP disclosed
EP-1776161-B1 COSMETIC OR DERMOPHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE UDP GLUCURONOSYL TRANSFERASE (UGT) ENZYMES INDUCER SEDERMA S A S (FR) 2016-10-26 EP disclosed
EP-1463793-B1 MIXTURES OF QUATERNARY COMPOUNDS CRODA INC (US) 2016-10-19 EP disclosed
EP-1435978-B1 ESTERS OF AROMATIC ALKOXYLATED ALCOHOLS AND FATTY CARBOXYLIC ACIDS CRODA INC (US) 2014-09-03 EP disclosed
US-8530426-B2 Topical use of a UGT inducer-containing composition comprising a dermatologically acceptable carrier to protect and/or enhance the state of the skin/hair and prevent and/or treat imperfections of the skin; flavanoids such as chrysin stimulates isoforms; protective coatings aging/ wrinkling resistance SEDERMA SAS (FR) 2013-09-10 US disclosed
US-20130129656-A1 \"GREEN\" DIESTER AMINES AND PERSONAL CARE PRODUCTS CRODA, INC. (US) 2013-05-23 US disclosed
US-8414906-B2 Additives and products including oligoesters CRODA, INC. (US) 2013-04-09 US disclosed
CN-1130864-A Personal cleansing compositions PROCTER & GAMBLE (US) 1996-09-11 CN disclosed
US-5539038-A Ink jet ink and process for making same REXHAM GRAPHICS, INC. (US) 1996-07-23 US disclosed
US-5534265-A INSOLUBILE POLYMER PARTICLES, GELLING AGENT, SURFACTANT, EMOLIENT THE PROCTER & GAMBLE COMPANY (US) 1996-07-09 US disclosed
EP-0714283-A1 PERSONAL CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1996-06-05 EP disclosed
WO-1996010603-A1 INK-JET INK AND PROCESS FOR MAKING SAME REXHAM GRAPHICS INC. (US) 1996-04-11 WO disclosed
WO-1996006595-A1 PERSONAL CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1996-03-07 WO disclosed
WO-1995003781-A1 PERSONAL CLEANSING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1995-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130129656-A1 \"GREEN\" DIESTER AMINES AND PERSONAL CARE PRODUCTS POLR1C, TYR, QARS1 THRB 3170/4885USP2 1424/4885ALDH1A1 730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.