Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | MC3R | P41968 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5062627 | 0.83 | KDM4E (0.61) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL1412848 | 0.81 | KDM4E (0.59) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL2310303 | 0.79 | KDM4E (0.59) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazine Carboxylic Acid Hydrazide SCHEMBL107341 | 0.79 | ADORA3 (0.61) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL30586327 | 0.79 | KDM4E (0.59) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL3715797 | 0.79 | KDM4E (0.57) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL27830128 | 0.79 | NPC1 (0.57) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL29132984 | 0.78 | GAA (0.55) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| Pyrazine Carboxylic Acid Hydrazide SCHEMBL18038330 | 0.78 | ADORA3 (0.59) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL29516859 | 0.76 | KDM4E (0.65) | KDM4ENAPRTHCAR2ADORA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190255009-A1 | STILBENE DERIVATIVE AND METHOD FOR PREPARING SAME | OZCHELA INC (KR) | 2019-08-22 | — | — | US | disclosed |
| US-20190248729-A1 | STILBENE DERIVATIVE AND METHOD FOR PREPARING SAME | Ozchela Inc. (KR) | 2019-08-15 | — | — | US | disclosed |
| WO-2010151797-A2 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | UNIVERSITY OF MASSACHUSETTS (US) | 2010-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190255009-A1 | STILBENE DERIVATIVE AND METHOD FOR PREPARING SAME | HPN, P4HB, FKBP1B | KDM4E 4629/4885NAPRT 919/4885HCAR2 1769/4885 |
| US-20190248729-A1 | STILBENE DERIVATIVE AND METHOD FOR PREPARING SAME | FKBP1B, FKBP8, FKBP2 | KDM4E 4277/4885NAPRT 1949/4885HCAR2 2268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.