Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139169 | 0.76 | APP (0.42) | MAPTMAPK1HSD17B10TSHRKDM4E | |
| SCHEMBL2140353 | 0.68 | APP (0.43) | MAPTMAPK1HSD17B10TSHRKDM4E | |
| SCHEMBL2136110 | 0.67 | APP (0.43) | MAPTMAPK1HSD17B10TSHRKDM4E | |
| SCHEMBL10285911 | 0.65 | — | — | |
| SCHEMBL10087223 | 0.65 | ALDH1A1 (0.37) | MAPTMAPK1HSD17B10TSHRKDM4E | |
| SCHEMBL2139176 | 0.61 | APP (0.40) | MAPTMAPK1HSD17B10TSHRKDM4E | |
| SCHEMBL10206317 | 0.61 | APP (0.45) | MAPTMAPK1HSD17B10TSHRKDM4E | |
| SCHEMBL2136872 | 0.59 | APP (0.50) | MAPTMAPK1TSHRKDM4EUSP2 | |
| SCHEMBL2141122 | 0.59 | ALDH1A1 (0.48) | MAPTHSD17B10TSHRKDM4EKMT2A | |
| SCHEMBL14869577 | 0.57 | MAPT (0.58) | MAPTMAPK1HSD17B10TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010149956-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-12-29 | — | — | WO | disclosed |