Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | AQP1 | P29972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10206317 | 0.91 | APP (0.45) | APPAQP1MAPTPOLBRAB9A | |
| SCHEMBL11902544 | 0.90 | APP (0.42) | APPAQP1MAPTPOLBRAB9A | |
| SCHEMBL2138062 | 0.90 | APP (0.42) | APPAQP1MAPTPOLBRAB9A | |
| SCHEMBL2138077 | 0.90 | APP (0.42) | APPAQP1MAPTPOLBRAB9A | |
| SCHEMBL2139169 | 0.90 | APP (0.42) | APPAQP1MAPTL3MBTL1TDP1 | |
| SCHEMBL2137670 | 0.89 | APP (0.44) | APPAQP1MAPTPOLBRAB9A | |
| SCHEMBL118741 | 0.86 | MAPT (0.39) | APPAQP1MAPTPOLBRAB9A | |
| SCHEMBL2712090 | 0.83 | APP (0.40) | APPAQP1MAPTPOLBRAB9A | |
| SCHEMBL2136872 | 0.81 | APP (0.50) | APPAQP1MAPTRAB9ATSHR | |
| SCHEMBL1917197 | 0.81 | ALDH1A1 (0.40) | MAPK1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445884-B1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA LTD (GB) | 2013-02-13 | — | — | EP | disclosed |
| EP-2445884-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Syngenta Limited (GB) | 2012-05-02 | — | — | EP | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-04-26 | — | — | US | disclosed |
| WO-2010149956-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010149956-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100990-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DDT, DAO, NPM1 | APP 2550/4885AQP1 1271/4885MAPT 1344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.