SCHEMBL1297498

SCHEMBL1297498

c1ccc2sc(-c3cccc4c3[nH]c3ccccc34)cc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.46
BCHE P06276 1/20 0.46
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
TUBB4A P04350 1/20 0.44
TUBB P07437 1/20 0.44
TUBA3C P0DPH7 1/20 0.44
TUBA1B P68363 1/20 0.44
TUBA4A P68366 1/20 0.44
TUBB4B P68371 1/20 0.44
TUBB3 Q13509 1/20 0.44
TUBB2A Q13885 1/20 0.44
TUBB8 Q3ZCM7 1/20 0.44
TUBA3E Q6PEY2 1/20 0.44
TUBA1A Q71U36 1/20 0.44
TUBA1C Q9BQE3 1/20 0.44
TUBB6 Q9BUF5 1/20 0.44
TUBB2B Q9BVA1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL29268829 0.91 BCHE (0.45) KIF11BCHEMEN1MAPTRAB9A
SCHEMBL31070704 0.77 NQO1 (0.54) APPCNR1NQO1NQO2PRKDC
SCHEMBL12405297 0.77 APP (0.53) APPCNR1NQO1NQO2PRKDC
SCHEMBL4868139 0.77 NQO1 (0.54) APPCNR1NQO1NQO2PRKDC
SCHEMBL6704319 0.75 KIF11 (0.51) KIF11BCHEMEN1MAPTRAB9A
SCHEMBL19133572 0.75 APP (0.57) APPNQO1NQO2HSD17B1HSD17B2
SCHEMBL208113 0.75 KIF11 (0.63) KIF11BCHEPARP14
SCHEMBL29733506 0.75 KIF11 (0.63) KIF11BCHEPARP14
SCHEMBL147411 0.74 BCHE (0.64) KIF11BCHEPARP14
SCHEMBL29986487 0.74 BCHE (0.64) KIF11BCHEPARP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119174304-A Photoelectric conversion element material for imaging and photoelectric conversion element for imaging using same 日铁化学材料株式会社 2024-12-20 CN disclosed
CN-118339941-A Mixed powder and method for producing same, method for producing organic electroluminescent element using same, method for selecting compound in mixed powder, and composition for vacuum vapor deposition 出光兴产株式会社 2024-07-12 CN disclosed
CN-109970768-B Based on carbazole eleven-membered condensed ring planar nucleus D (A-Ar)2Organic photoelectric compound, preparation method and application 常州大学 2020-12-25 CN disclosed
US-20150280147-A1 AROMATIC AZA-BICYCLIC COMPOUNDS CONTAINING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-10-01 US disclosed
US-20150280147-A1 AROMATIC AZA-BICYCLIC COMPOUNDS CONTAINING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-10-01 US disclosed
US-20150280147-A1 AROMATIC AZA-BICYCLIC COMPOUNDS CONTAINING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-10-01 US disclosed
EP-2906567-A1 AROMATIC AZA-BICYCLIC COMPOUNDS COMPRISING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2015-08-19 EP disclosed
WO-2014067598-A1 AROMATIC AZA-BICYCLIC COMPOUNDS COMPRISING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-05-08 WO disclosed
WO-2014067598-A1 AROMATIC AZA-BICYCLIC COMPOUNDS COMPRISING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-05-08 WO disclosed
US-8637857-B2 Substituted carbazole derivatives and use thereof in organic electronics BASF SE (DE) 2014-01-28 US disclosed
EP-2556075-A1 SUBSTITUTED CARBAZOLE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2013-02-13 EP disclosed
CN-102933582-A Substituted carbazole derivatives and their use in organic electronic devices BASF SE 2013-02-13 CN disclosed
US-20110266528-A1 SUBSTITUTED CARBAZOLE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2011-11-03 US disclosed
WO-2011125020-A1 SUBSTITUTED CARBAZOLE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2011-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150280147-A1 AROMATIC AZA-BICYCLIC COMPOUNDS CONTAINING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES AOC2, AOC1, AOC3 KIF11 3369/4885BCHE 1731/4885MEN1 4072/4885
US-20110266528-A1 SUBSTITUTED CARBAZOLE DERIVATIVES AND USE THEREOF IN ORGANIC ELECTRONICS NR2E3, CHRNA5, CHRNA4 KIF11 4107/4885BCHE 4227/4885MEN1 2201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.