SCHEMBL1297690

SCHEMBL1297690

O=C(O)C1CCC(C(=O)OCCO)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
PLG P00747 1/20 0.42
PLAT P00750 1/20 0.42
PPM1B O75688 2/20 0.39
PTPN1 P18031 2/20 0.39
PPP1CC P36873 2/20 0.39
TSHR P16473 2/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
GABRA2 P47869 1/20 0.37
GABRB2 P47870 1/20 0.37
GABRA4 P48169 1/20 0.37
GABRE P78334 1/20 0.37
PMP22 Q01453 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30368740 0.91 TSHR (0.39) LMNAPPM1BPTPN1PPP1CCTSHR
SCHEMBL21357046 0.91
SCHEMBL30368963 0.91 TSHR (0.39) LMNAPPM1BPTPN1PPP1CCTSHR
SCHEMBL1297693 0.91 TSHR (0.39) LMNAPPM1BPTPN1PPP1CCTSHR
SCHEMBL8548602 0.89 LMNA (0.46) LMNAPLGPLATPPM1BPTPN1
SCHEMBL1295731 0.89 MEN1 (0.39) LMNAPLGPLATPPM1BPTPN1
SCHEMBL28459067 0.86 PLG (0.38) LMNAPLGPLATPPM1BPTPN1
Ethylene Glycol SCHEMBL1297766 0.85 PPM1B (0.53) LMNAPLGPLATPPM1BPTPN1
SCHEMBL17085312 0.83 LMNA (0.42) LMNAPLGPLATPPM1BPTPN1
SCHEMBL15071089 0.83 NPC1 (0.36) PPM1BPTPN1PPP1CCTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023163544-A1 PLASTICIZER COMPOSITION AND RESIN COMPOSITION COMPRISING SAME 주식회사 엘지화학 2023-08-31 WO disclosed
WO-2023163546-A1 PLASTICIZER COMPOSITION AND RESIN COMPOSITION COMPRISING SAME 주식회사 엘지화학 2023-08-31 WO disclosed
WO-2023163545-A1 PLASTICIZER COMPOSITION AND RESIN COMPOSITION COMPRISING SAME 주식회사 엘지화학 2023-08-31 WO disclosed
CN-115651369-A Novel polyester film, preparation method thereof and high-resistance Gao Chong deep aluminum-plastic composite film 浙江华正能源材料有限公司 2023-01-31 CN disclosed
CN-115651369-A Novel polyester film, preparation method thereof and high-resistance Gao Chong deep aluminum-plastic composite film 浙江华正能源材料有限公司 2023-01-31 CN disclosed
US-20210228462-A1 COMPOSITION FOR DYEING LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2021-07-29 US disclosed
US-20170009046-A1 Graphene Reinforced Polyethylene Terephthalate WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2017-01-12 US disclosed
US-8889748-B2 Process for producing expandable styrene polymer compositions BASF SE (DE) 2014-11-18 US disclosed
US-8454744-B2 Use of polyols and cyclohexane polycarboxylic acid derivatives for the removal of dust from chemical construction products CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-06-04 US disclosed
US-20120138206-A1 ADHESIVES AND SEALANTS CONTAINING CYCLOHEXANE POLYCARBOXYLIC ACID DERIVATIVES BASF SE (DE) 2012-06-07 US disclosed
US-20110291040-A1 PROCESS FOR PRODUCING EXPANDABLE STYRENE POLYMER COMPOSITIONS BASF SE (DE) 2011-12-01 US disclosed
US-20110265693-A1 Use Of Polyols And Cyclohexane Polycarboxylic Acid Derivatives For The Removal Of Dust From Chemical Construction Products Construction Research & Tecnology GMBH (DE) 2011-11-03 US disclosed
US-7337913-B2 Single piece closure device made of PVC BASF AKTIENGESELLSCHAFT (DE) 2008-03-04 US disclosed
US-20050106405-A1 Single piece closure device made of pvc BASF AKTIENGESELLSCHAFT (DE) 2005-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210228462-A1 COMPOSITION FOR DYEING TYR, CUTA, KRT18 LMNA 1185/4885PLG 772/4885PLAT 2915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.