SCHEMBL1297693

SCHEMBL1297693

O=C(OCCO)C1CCC(C(=O)OCCO)CC1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
MAPT P10636 3/20 0.36
RAB9A P51151 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
NPC1 O15118 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PPM1B O75688 1/20 0.35
PTPN1 P18031 1/20 0.35
PPP1CC P36873 1/20 0.35
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.33
LMNA P02545 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21357046 1.00
SCHEMBL30368740 1.00 TSHR (0.39) TSHRMAPTRAB9AL3MBTL1NPC1
SCHEMBL30368963 1.00 TSHR (0.39) TSHRMAPTRAB9AL3MBTL1NPC1
SCHEMBL15071089 0.91 NPC1 (0.36) TSHRMAPTRAB9AL3MBTL1NPC1
SCHEMBL1297690 0.91 LMNA (0.42) TSHRMAPTRAB9AL3MBTL1NPC1
SCHEMBL27699230 0.91 SMN1; SMN2 (0.42) TSHRMAPTL3MBTL1HTTSMN1; SMN2
SCHEMBL1297418 0.89 MAPT (0.50) MAPTPPM1BPTPN1PPP1CCALDH1A1
SCHEMBL1297364 0.89 GAA (0.44) MAPTRAB9AL3MBTL1NPC1SMN1; SMN2
SCHEMBL1297774 0.89 PPM1B (0.49) TSHRMAPTSMN1; SMN2PPM1BPTPN1
SCHEMBL3404743 0.89 ALDH1A1 (0.46) MAPTL3MBTL1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107417526-B Process for preparing 1,4-cyclohexane dicarboxylic acid dihydroxy ethyl ester and its derivative 远东新世纪股份有限公司 2020-09-25 CN claimed
US-10017454-B2 Method of manufacturing BHCD and derivatives thereof FAR EASTERN NEW CENTURY CORPORATION (TW) 2018-07-10 US claimed
US-20170342016-A1 METHOD OF MANUFACTURING BHCD AND DERIVATIVES THEREOF FAR EASTERN NEW CENTURY CORPORATION (TW) 2017-11-30 US claimed
WO-2023163544-A1 PLASTICIZER COMPOSITION AND RESIN COMPOSITION COMPRISING SAME 주식회사 엘지화학 2023-08-31 WO disclosed
WO-2023163546-A1 PLASTICIZER COMPOSITION AND RESIN COMPOSITION COMPRISING SAME 주식회사 엘지화학 2023-08-31 WO disclosed
WO-2023163545-A1 PLASTICIZER COMPOSITION AND RESIN COMPOSITION COMPRISING SAME 주식회사 엘지화학 2023-08-31 WO disclosed
EP-3533779-B1 PRODUCTION METHOD FOR TRANS-BIS(2-HYDROXYALKYL) CYCLOHEXANEDICARBOXYLATE, AND BIS(2-HYDROXYALKYL) CYCLOHEXANEDICARBOXYLATE JEPLAN INC (JP) 2023-04-05 EP disclosed
US-20210228462-A1 COMPOSITION FOR DYEING LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2021-07-29 US disclosed
CN-107417526-B Process for preparing 1,4-cyclohexane dicarboxylic acid dihydroxy ethyl ester and its derivative 远东新世纪股份有限公司 2020-09-25 CN disclosed
US-10017454-B2 Method of manufacturing BHCD and derivatives thereof FAR EASTERN NEW CENTURY CORPORATION (TW) 2018-07-10 US disclosed
US-10017454-B2 Method of manufacturing BHCD and derivatives thereof FAR EASTERN NEW CENTURY CORPORATION (TW) 2018-07-10 US disclosed
US-8889748-B2 Process for producing expandable styrene polymer compositions BASF SE (DE) 2014-11-18 US disclosed
US-8454744-B2 Use of polyols and cyclohexane polycarboxylic acid derivatives for the removal of dust from chemical construction products CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-06-04 US disclosed
US-20120138206-A1 ADHESIVES AND SEALANTS CONTAINING CYCLOHEXANE POLYCARBOXYLIC ACID DERIVATIVES BASF SE (DE) 2012-06-07 US disclosed
US-20110291040-A1 PROCESS FOR PRODUCING EXPANDABLE STYRENE POLYMER COMPOSITIONS BASF SE (DE) 2011-12-01 US disclosed
US-20110265693-A1 Use Of Polyols And Cyclohexane Polycarboxylic Acid Derivatives For The Removal Of Dust From Chemical Construction Products Construction Research & Tecnology GMBH (DE) 2011-11-03 US disclosed
US-7337913-B2 Single piece closure device made of PVC BASF AKTIENGESELLSCHAFT (DE) 2008-03-04 US disclosed
US-20050106405-A1 Single piece closure device made of pvc BASF AKTIENGESELLSCHAFT (DE) 2005-05-19 US disclosed
US-20030036620-A1 From an aromatic isocyanate having a structure in which the isocyanate groups are not directly bonded to a benzene ring, an aliphatic isocyanate, an alicyclic isocyanate, and derivatives of these isocyanates. MITSUI CHEMICALS, INC. (JP) 2003-02-20 US disclosed
EP-1167416-A1 URETHANE RESIN COMPOSITION FOR SEALING OPTOELECTRIC CONVERSION DEVICES Mitsui Chemicals, Inc. (JP) 2002-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170342016-A1 METHOD OF MANUFACTURING BHCD AND DERIVATIVES THEREOF BHMT, BHMT2, HPD TSHR 3767/4885MAPT 932/4885RAB9A 2046/4885
US-20210228462-A1 COMPOSITION FOR DYEING TYR, CUTA, KRT18 TSHR 3133/4885MAPT 1043/4885RAB9A 4120/4885
US-10017454-B2 Method of manufacturing BHCD and derivatives thereof BHMT, BHMT2, HPD TSHR 3767/4885MAPT 932/4885RAB9A 2046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.