Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.52 |
| ▸ | POLQ | O75417 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791972 | 0.84 | MLYCD (0.52) | MLYCDTRPV1NR1H3POLQKDM4E | |
| SCHEMBL12978252 | 0.83 | MLYCD (0.56) | MLYCDTRPV1NR1H3POLQNR1H2 | |
| SCHEMBL12977968 | 0.79 | TRPV1 (0.55) | MLYCDTRPV1NR1H3POLQNR1H2 | |
| SCHEMBL12978272 | 0.79 | TRPV1 (0.55) | MLYCDTRPV1NR1H3KDM4EKMT2A | |
| SCHEMBL6237453 | 0.78 | KDM4E (0.68) | MLYCDTRPV1NR1H3NR1H2KDM4E | |
| SCHEMBL12977958 | 0.78 | TRPV1 (0.54) | MLYCDTRPV1NR1H3POLQKDM4E | |
| SCHEMBL12978248 | 0.78 | MLYCD (0.55) | MLYCDTRPV1NR1H3POLQNR1H2 | |
| SCHEMBL96022 | 0.77 | TRPV1 (0.62) | MLYCDTRPV1NR1H3POLQKDM4E | |
| SCHEMBL7377948 | 0.77 | TRPV1 (0.62) | MLYCDTRPV1NR1H3KDM4EKMT2A | |
| SCHEMBL12978265 | 0.77 | GPBAR1 (0.61) | MLYCDTRPV1POLQKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | MLYCD 654/4885TRPV1 2769/4885NR1H3 4005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.