Sugi Predict

Sugi Predict / Compounds / SCHEMBL12984646

SCHEMBL12984646

SCHEMBL12984646

CSCC[C@H](NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O)[C@@H](C)O

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ RAMP3 O60896 15/20 0.63
▸ CALCR P30988 15/20 0.63
▸ APLNR P35414 1/20 0.54
▸ PIN1 Q13526 1/20 0.53
▸ TFPI P10646 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12984102 0.88 RAMP3 (0.66) RAMP3CALCRAPLNRTFPI
SCHEMBL13027243 0.85 RAMP3 (0.62) RAMP3CALCRAPLNRTFPI
SCHEMBL13028816 0.84 TFPI (0.62) RAMP3CALCRTFPI
SCHEMBL22423719 0.80 RAMP3 (0.56) RAMP3CALCRPIN1TFPI
SCHEMBL24601727 0.80 GLP1R (0.60) —
SCHEMBL26346380 0.80 GLP1R (0.60) —
SCHEMBL10066201 0.80 PRSS1 (0.49) RAMP3CALCRAPLNRPIN1
SCHEMBL10066224 0.79 RAMP3 (0.51) RAMP3CALCR
SCHEMBL10066203 0.78 RAMP3 (0.60) RAMP3CALCRTFPI
SCHEMBL12984108 0.78 RAMP3 (0.62) RAMP3CALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100316563-A1 Method For The Preparation Of New Oligoclonal Antibodies BRACCO IMAGING S.P.A. (IT) 2010-12-16 — — US disclosed
US-20100316563-A1 Method For The Preparation Of New Oligoclonal Antibodies BRACCO IMAGING S.P.A. (IT) 2010-12-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100316563-A1 Method For The Preparation Of New Oligoclonal Antibodies APOB, APOL1, FCGR3B RAMP3 3589/4885CALCR 1054/4885APLNR 443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback