Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702627 | 0.93 | TSHR (0.54) | ALDH1A1TSHRTP53SRD5A2GAA | |
| SCHEMBL4814685 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRTP53SRD5A2KMT2A | |
| Terephthalic Acid SCHEMBL166042 | 0.81 | TSHR (0.92) | ALDH1A1TSHRTP53SRD5A2CA1 | |
| SCHEMBL8875452 | 0.80 | ALDH1A1 (0.60) | ALDH1A1TSHRTP53SRD5A2KMT2A | |
| SCHEMBL5546768 | 0.79 | ALDH1A1 (0.61) | ALDH1A1SRD5A2KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL70166 | 0.79 | TSHR (0.67) | ALDH1A1TSHRTP53SRD5A2KMT2A | |
| SCHEMBL68390 | 0.79 | SRD5A2 (0.69) | ALDH1A1TSHRTP53SRD5A2KMT2A | |
| Terephthalic Acid SCHEMBL4612225 | 0.79 | TSHR (0.67) | ALDH1A1TSHRTP53SRD5A2KMT2A | |
| SCHEMBL297476 | 0.79 | RXRA (0.62) | ALDH1A1TSHRTP53SRD5A2KMT2A | |
| SCHEMBL2537663 | 0.78 | PLA2G10 (0.57) | ALDH1A1TSHRKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112752756-B | Tetrahydro-imidazo [4,5-c ] pyridine derivatives as PD-L1 immunomodulators | 因赛特公司 | 2024-06-25 | — | — | CN | claimed |
| EP-4219492-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | Incyte Corporation (US) | 2023-08-02 | — | — | EP | claimed |
| EP-3790877-B1 | TETRAHYDRO-IMIDAZO[4,5-C]PYRIDINE DERIVATIVES AS PD-L1 IMMUNOMODULATORS | INCYTE CORP (US) | 2023-03-01 | — | — | EP | claimed |
| US-20220348594-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2022-11-03 | — | — | US | claimed |
| CN-112752756-A | Tetrahydro-imidazo [4,5-c ] pyridine derivatives as PD-L1 immunomodulators | 因赛特公司 | 2021-05-04 | — | — | CN | claimed |
| US-20210115068-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2021-04-22 | — | — | US | claimed |
| EP-3790877-A1 | TETRAHYDRO-IMIDAZO[4,5-C]PYRIDINE DERIVATIVES AS PD-L1 IMMUNOMODULATORS | Incyte Corporation (US) | 2021-03-17 | — | — | EP | claimed |
| US-10906920-B2 | Heterocyclic compounds as immunomodulators | INCYTE CORPORATION (US) | 2021-02-02 | — | — | US | claimed |
| US-20200397893-A1 | IMMUNOMODULATOR COMPOUNDS AND METHODS OF USE | INCYTE CORPORATION | 2020-12-24 | — | — | US | claimed |
| US-20200277309-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION | 2020-09-03 | — | — | US | claimed |
| US-5695909-A | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1997-12-09 | — | — | US | claimed |
| EP-0591786-B1 | Photosensitive composition | FUJI PHOTO FILM CO LTD (JP) | 1996-05-15 | — | — | EP | claimed |
| EP-0368327-B1 | Light-sensitive composition | FUJI PHOTO FILM CO LTD (JP) | 1995-02-15 | — | — | EP | claimed |
| CN-1094035-A | Carboxylic acid derivative contains pharmaceutical composition of these compounds and preparation method thereof | THOMAE GMBH DR K (DE) | 1994-10-26 | — | — | CN | claimed |
| EP-0591786-A2 | Photosensitive composition | FUJI PHOTO FILM CO., LTD. (JP) | 1994-04-13 | — | — | EP | claimed |
| US-5202221-A | Photocrosslinkable copolymer having maleimido side chain, cyanine dye sensitizer | FUJI PHOTO FILM CO., LTD. (JP) | 1993-04-13 | — | — | US | claimed |
| EP-0368327-A2 | Light-sensitive composition | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-16 | — | — | EP | claimed |
| US-4239850-A | PHOTOINITIATOR OF AN UNSATURATED KETONE AND A TRIHALOMETHYL TRIAZINE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-12-16 | — | — | US | claimed |
| US-3988513-A | CYANINE DYE | FUJI PHOTO FILM CO., LTD. (JA) | 1976-10-26 | — | — | US | claimed |
| US-3933800-A | O-SUBSTITUTED OXIMES, MICROBIOCIDES | GRUPPO LEPETIT S.P.A. (IT) | 1976-01-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10906920-B2 | Heterocyclic compounds as immunomodulators | CD74, IL2, ICOS | ALDH1A1 223/4885TSHR 2482/4885TP53 180/4885 |
| US-20210115068-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | CD74, IL2, ICOS | ALDH1A1 223/4885TSHR 2482/4885TP53 180/4885 |
| US-20200277309-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | CD74, IL2, ICOS | ALDH1A1 223/4885TSHR 2482/4885TP53 180/4885 |
| US-20220348594-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | CD74, IL2, ICOS | ALDH1A1 223/4885TSHR 2482/4885TP53 180/4885 |
| US-20200397893-A1 | IMMUNOMODULATOR COMPOUNDS AND METHODS OF USE | CD274, PDCD1LG2, PDCD1 | ALDH1A1 1759/4885TSHR 573/4885TP53 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.