Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.92 |
| ▸ | TP53 | P04637 | 1/20 | 0.92 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.75 |
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA3 | P07451 | 1/20 | 0.71 |
| ▸ | TYR | P14679 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.69 |
| ▸ | DAO | P14920 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL175823 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL25381766 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL156613 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1151273 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL21443891 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20704876 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5969822 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113789039-B | Biodegradable polyester heat shrinkable film and preparation method thereof | 江苏景宏新材料科技有限公司 | 2022-06-14 | — | — | CN | claimed |
| CN-113789039-A | Biodegradable polyester heat shrinkable film and preparation method thereof | 江苏景宏新材料科技有限公司 | 2021-12-14 | — | — | CN | claimed |
| CN-111333973-B | Anti-aging laminating film | 江苏金材科技有限公司 | 2021-09-10 | — | — | CN | claimed |
| CN-111333973-A | Anti-aging laminating film | 江苏金材科技有限公司 | 2020-06-26 | — | — | CN | claimed |
| CN-110922728-A | Organic nucleating agent for preparing heat-resistant polylactic resin and preparation method thereof | 蚌埠学院 | 2020-03-27 | — | — | CN | claimed |
| CN-110684246-A | Tread rubber of low-saturation pattern oil-resistant tire and preparation method thereof | 徐州徐轮橡胶有限公司 | 2020-01-14 | — | — | CN | claimed |
| CN-104086803-B | A kind of rubber anti-ageing agent | CHANGZHOU WUZHOU CHEMICAL CO., LTD. (CN) | 2016-06-01 | — | — | CN | claimed |
| CN-103819825-B | A kind of production method of environment-friendly type butyl reclaimed rubber | JIANGSU ATE POLYMER MATERIALS CO., LTD. (CN) | 2016-04-13 | — | — | CN | claimed |
| CN-104072823-B | A kind of rubber antioxidant | CHANGZHOU WUZHOU CHEMICAL CO., LTD. (CN) | 2016-03-23 | — | — | CN | claimed |
| CN-103980574-B | A kind of modified butadiene acrylonitrile rubber and preparation method thereof | CHANGZHOU WUZHOU CHEMICAL CO., LTD. (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-102134332-A | Rubber-plastic fire retardant composition, fire retardant rubber and plastic and preparation thereof | JIANGSU ANTI AGING POLYMER MATERIAL CO LTD | 2011-07-27 | — | — | CN | claimed |
| CN-102108194-A | Polylactic acid/fatty dibasic acid and diol polyester composite | TORAY FIBER RES INST CN CO LTD | 2011-06-29 | — | — | CN | claimed |
| CN-102061022-A | Novel rubber activator and preparation method thereof | JIANGSU AITEEN MACROMOLECULE MARTIAL CO LTD | 2011-05-18 | — | — | CN | claimed |
| CN-102061023-A | Novel rubber antioxidant and preparation method thereof | JIANGSU AITEEN MACROMOLECULE MARTIAL CO LTD | 2011-05-18 | — | — | CN | claimed |
| EP-0478199-B1 | Polyvinyl chloride resin composition for powder molding | SUMITOMO CHEMICAL CO (JP) | 1997-06-25 | — | — | EP | claimed |
| EP-0478199-A2 | Polyvinyl chloride resin composition for powder molding | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-04-01 | — | — | EP | claimed |
| CN-1012682-B | POLYVINYL CHLORIDE RESIN COMPOSITION FOR POWDER MOLDING | SUMITOMO CHEMICAL CO (JP) | 1991-05-29 | — | — | CN | claimed |
| US-4861816-A | Polyvinyl chloride resin composition for powder molding | SUMITOMO CHEMICAL COMPANY (JP) | 1989-08-29 | — | — | US | claimed |
| CN-87105970-A | The poly (vinyl chloride) resin composition that is used for powder molding | — | 1988-08-10 | — | — | CN | claimed |
| US-4198458-A | MAGNETIC TAPES | TEIJIN LIMITED (JP) | 1980-04-15 | — | — | US | claimed |