Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072154 | 0.85 | ABL1 (0.38) | — | |
| SCHEMBL11072203 | 0.85 | ABL1 (0.38) | — | |
| SCHEMBL15759685 | 0.81 | TLR4 (0.33) | TLR4 | |
| SCHEMBL11028194 | 0.78 | ABL1 (0.41) | — | |
| SCHEMBL13259644 | 0.76 | ALDH1A1 (0.41) | PAOX | |
| SCHEMBL13528880 | 0.74 | PAOX (0.45) | PAOXSMN1; SMN2 | |
| SCHEMBL19043252 | 0.74 | CES2 (0.41) | PAOX | |
| SCHEMBL1092222 | 0.74 | ALDH1A1 (0.36) | SMN1; SMN2 | |
| 2-Decanone SCHEMBL10631997 | 0.73 | NAAA (0.53) | — | |
| Acetic Acid SCHEMBL29124335 | 0.71 | ACE (0.37) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139827-A1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | LABORATORIOS SALVAT, S.A. (ES) | 2010-12-09 | — | — | WO | disclosed |