SCHEMBL12986232

SCHEMBL12986232

Cc1ccc(O)c([C@H](CCN(C(C)C)C(C)C)c2ccccc2)c1Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 9/20 0.54
CHRM2 P08172 3/20 0.54
CHRM1 P11229 3/20 0.54
HRH1 P35367 3/20 0.54
MAPT P10636 3/20 0.54
CHRM5 P08912 2/20 0.54
HTR2A P28223 2/20 0.54
LMNA P02545 2/20 0.54
ESR1 P03372 1/20 0.54
CHRM4 P08173 1/20 0.54
KCNE1 P15382 1/20 0.54
PTGS1 P23219 1/20 0.54
HRH2 P25021 1/20 0.54
SLC6A4 P31645 1/20 0.54
ADRA1A P35348 1/20 0.54
OPRK1 P41145 1/20 0.54
KCNQ1 P51787 1/20 0.54
KCNH2 Q12809 1/20 0.54
CACNA1C Q13936 1/20 0.54
SCN5A Q14524 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1496992 0.88 CHRM3 (0.56) CHRM3CHRM2CHRM1HRH1MAPT
SCHEMBL19212507 0.82 CHRM3 (0.51) CHRM3CHRM2CHRM1HRH1MAPT
SCHEMBL724557 0.80 CHRM3 (0.63) CHRM3CHRM2CHRM1HRH1MAPT
SCHEMBL724558 0.80 CHRM3 (0.63) CHRM3CHRM2CHRM1HRH1MAPT
SCHEMBL14988049 0.79 CHRM3 (0.58) CHRM3CHRM2CHRM1HRH1MAPT
SCHEMBL6757073 0.74 CHRM3 (0.55) CHRM3CHRM2CHRM1HRH1MAPT
SCHEMBL1809355 0.74 CHRM3 (0.55) CHRM3CHRM2CHRM1HRH1MAPT
SCHEMBL1809358 0.74 CHRM3 (0.55) CHRM3CHRM2CHRM1HRH1MAPT
SCHEMBL5614313 0.74 CHRM3 (0.65) CHRM3CHRM2CHRM1HRH1MAPT
SCHEMBL3770623 0.73 CHRM3 (0.54) CHRM3CHRM2CHRM1HRH1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315450-B2 Desfesoterodine salts RATIOPHARM GMBH (DE) 2016-04-19 US disclosed
EP-2800735-B1 PROCESS FOR THE PREPARATION OF FESOTERODINE ALEMBIC PHARMACEUTICALS LTD (IN) 2016-03-30 EP disclosed
EP-2760822-B1 DESFESOTERODINE SALTS RATIOPHARM GMBH (DE) 2016-03-23 EP disclosed
US-9085509-B2 Process for preparing fesoterodine ALEMBIC PHARMACEUTICALS LIMITED (IN) 2015-07-21 US disclosed
US-20150152044-A1 DESFESOTERODINE SALTS RATIOPHARM GMBH (DE) 2015-06-04 US disclosed
EP-2686288-B1 A PROCESS FOR PREPARING FESOTERODINE ALEMBIC PHARMACEUTICALS LTD (IN) 2015-03-25 EP disclosed
US-20140378699-A1 PROCESS FOR THE PREPARATION OF FESOTERODINE ALEMBIC PHARMACEUTICALS LIMITED (IN) 2014-12-25 US disclosed
EP-2800735-A2 PROCESS FOR THE PREPARATION OF FESOTERODINE Alembic Pharmaceuticals Limited (IN) 2014-11-12 EP disclosed
EP-2760822-A1 DESFESOTERODINE SALTS Ratiopharm GmbH (DE) 2014-08-06 EP disclosed
US-20140039216-A1 PROCESS FOR PREPARING FESOTERODINE ALEMBIC PHARMACEUTICALS LIMITED (IN) 2014-02-06 US disclosed
EP-2686288-A1 A PROCESS FOR PREPARING FESOTERODINE Alembic Pharmaceuticals Limited (IN) 2014-01-22 EP disclosed
EP-2686288-A1 A PROCESS FOR PREPARING FESOTERODINE Alembic Pharmaceuticals Limited (IN) 2014-01-22 EP disclosed
WO-2013188829-A1 DESFESOTERODINE SALTS RATIOPHARM GMBH (DE) 2013-12-19 WO disclosed
WO-2013035084-A2 PROCESS FOR THE PREPARATION OF FESOTERODINE ALEMBIC PHARMACEUTICALS LIMITED (IN) 2013-03-14 WO disclosed
WO-2012137047-A1 A PROCESS FOR PREPARING FESOTERODINE ALEMBIC PHARMACEUTICALS LIMITED (IN) 2012-10-11 WO disclosed
WO-2012137047-A1 A PROCESS FOR PREPARING FESOTERODINE ALEMBIC PHARMACEUTICALS LIMITED (IN) 2012-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140378699-A1 PROCESS FOR THE PREPARATION OF FESOTERODINE MAOB, NISCH, TES CHRM3 66/4885CHRM2 265/4885CHRM1 668/4885
US-20140039216-A1 PROCESS FOR PREPARING FESOTERODINE FES, QDPR, CYP4F3 CHRM3 220/4885CHRM2 417/4885CHRM1 940/4885
US-20150152044-A1 DESFESOTERODINE SALTS TES, SYMPK, ADRB3 CHRM3 88/4885CHRM2 223/4885CHRM1 433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.