Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.63 |
| ▸ | HRH1 | P35367 | 4/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.63 |
| ▸ | HTR2A | P28223 | 3/20 | 0.63 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | HRH2 | P25021 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.63 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.63 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL724557 | 1.00 | CHRM3 (0.63) | CHRM3CHRM2HRH1CHRM1HTR2A | |
| SCHEMBL1809358 | 0.87 | CHRM3 (0.55) | CHRM3CHRM2HRH1CHRM1HTR2A | |
| SCHEMBL1809355 | 0.87 | CHRM3 (0.55) | CHRM3CHRM2HRH1CHRM1HTR2A | |
| SCHEMBL6757073 | 0.87 | CHRM3 (0.55) | CHRM3CHRM2HRH1CHRM1HTR2A | |
| SCHEMBL3770623 | 0.86 | CHRM3 (0.54) | CHRM3CHRM2HRH1CHRM1HTR2A | |
| SCHEMBL6760485 | 0.85 | CHRM3 (0.56) | CHRM3CHRM2HRH1CHRM1HTR2A | |
| SCHEMBL14988049 | 0.84 | CHRM3 (0.58) | CHRM3CHRM2HRH1CHRM1HTR2A | |
| SCHEMBL6763951 | 0.83 | CHRM3 (0.51) | CHRM3CHRM2HRH1CHRM1HTR2A | |
| SCHEMBL15141230 | 0.82 | CHRM3 (0.50) | CHRM3CHRM2HRH1CHRM1HTR2A | |
| SCHEMBL1496992 | 0.82 | CHRM3 (0.56) | CHRM3CHRM2HRH1CHRM1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012678-B2 | Processes for the preparation of fesoterodine | CADILA HEALTHCARE LIMITED (IN) | 2015-04-21 | — | — | US | claimed |
| US-20130197260-A1 | PROCESSES FOR THE PREPARATION OF FESOTERODINE | CADILA HEALTHCARE LIMITED (IN) | 2013-08-01 | — | — | US | claimed |
| WO-2012025941-A2 | PROCESSES FOR THE PREPARATION OF FESOTERODINE | CADILA HEALTHCARE LIMITED (IN) | 2012-03-01 | — | — | WO | claimed |
| US-9012678-B2 | Processes for the preparation of fesoterodine | CADILA HEALTHCARE LIMITED (IN) | 2015-04-21 | — | — | US | disclosed |
| US-20130197260-A1 | PROCESSES FOR THE PREPARATION OF FESOTERODINE | CADILA HEALTHCARE LIMITED (IN) | 2013-08-01 | — | — | US | disclosed |
| US-20110282094-A1 | PROCESS FOR PREPARATION OF PHENOLIC MONOESTERS OF HYDROXYMETHYL PHENOLS | INTAS PHARMACEUTICALS LIMITED (IN) | 2011-11-17 | — | — | US | disclosed |
| US-20110124903-A1 | SOLID STATE FORMS OF FESOTERODINE INTERMEDIATES | ACTAVIS GROUP PTC EHF (IS) | 2011-05-26 | — | — | US | disclosed |
| US-20100217034-A1 | Process for the Preparation of Fesoterodine | ACTAVIS GROUP PTC EHF (IS) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197260-A1 | PROCESSES FOR THE PREPARATION OF FESOTERODINE | QDPR, FES, SULT1A1 | CHRM3 203/4885CHRM2 211/4885HRH1 435/4885 |
| US-20110282094-A1 | PROCESS FOR PREPARATION OF PHENOLIC MONOESTERS OF HYDROXYMETHYL PHENOLS | HPD, COMT, PNMT | CHRM3 2337/4885CHRM2 1605/4885HRH1 261/4885 |
| US-20100217034-A1 | Process for the Preparation of Fesoterodine | ADRB3, FES, QDPR | CHRM3 41/4885CHRM2 107/4885HRH1 401/4885 |
| US-20110124903-A1 | SOLID STATE FORMS OF FESOTERODINE INTERMEDIATES | FES, NISCH, RPS27A | CHRM3 294/4885CHRM2 530/4885HRH1 1344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.