Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13993954 | 0.82 | ALDH1A1 (0.45) | ALDH1A1LMNASLC15A2PAOXACHE | |
| SCHEMBL11512604 | 0.80 | ADRA1A (0.40) | ALDH1A1LMNASLC15A2KDM4EKDM6B | |
| SCHEMBL7084623 | 0.74 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL9790222 | 0.74 | — | — | |
| SCHEMBL22351999 | 0.73 | ALDH1A1 (0.36) | ALDH1A1LMNASLC15A2GAA | |
| SCHEMBL13518683 | 0.73 | ALDH1A1 (0.36) | ALDH1A1LMNASLC15A2PAOXGAA | |
| SCHEMBL13180634 | 0.72 | GAA (0.48) | ALDH1A1GAA | |
| SCHEMBL17087048 | 0.70 | — | — | |
| SCHEMBL14878450 | 0.70 | PAOX (0.33) | ALDH1A1PAOX | |
| SCHEMBL14946895 | 0.69 | ALDH1A1 (0.56) | ALDH1A1LMNASLC15A2PAOXACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7847034-B2 | Adducts and curable compositions using same | LOCTITE (R&D) LIMITED (IE) | 2010-12-07 | — | — | US | disclosed |