Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KDM5C | P41229 | 3/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.39 |
| ▸ | KDM6B | O15054 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10800659 | 0.85 | ADRA1A (0.40) | ADRA1AHMGCRCHRM1TBXA2RNAALAD2 | |
| SCHEMBL1983625 | 0.82 | LMNA (0.40) | ADRA1AHMGCRCHRM1TBXA2RNAALAD2 | |
| Hydrochloric Acid SCHEMBL2653260 | 0.80 | NAALAD2 (0.39) | ADRA1AHMGCRCHRM1TBXA2RNAALAD2 | |
| SCHEMBL12986940 | 0.80 | ALDH1A1 (0.43) | EGLN1KDM4EKDM5CPHF8KDM2A | |
| SCHEMBL7566798 | 0.77 | LMNA (0.40) | ADRA1AEGLN1KDM4EKDM5CPHF8 | |
| SCHEMBL12227932 | 0.76 | NAALAD2 (0.36) | ADRA1AHMGCRCHRM1TBXA2RNAALAD2 | |
| SCHEMBL12227731 | 0.76 | EGLN1 (0.41) | ADRA1ANAALAD2EGLN1KDM4EKDM5C | |
| SCHEMBL25547365 | 0.76 | FFAR3 (0.40) | NAALAD2EGLN1LMNAALKBH5SUCNR1 | |
| SCHEMBL10799064 | 0.76 | — | — | |
| SCHEMBL9065250 | 0.75 | POLB (0.39) | ADRA1ANAALAD2EGLN1KDM4EKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171424-A | Polyesters containing units derived from metal salts of N-hydroxyalkylated branched α-aminoacids | CIBA-GEIGY CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4093639-A | HEAT RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |