Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12017474 | 0.80 | APP (0.37) | MEN1KMT2AAPPMAPT | |
| SCHEMBL9132731 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1MAPTLTA4H | |
| SCHEMBL12987122 | 0.76 | HTT (0.35) | MAPT | |
| SCHEMBL3327880 | 0.74 | MAPT (0.40) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3060051 | 0.73 | MAOB (0.51) | APPALDH1A1MAPT | |
| SCHEMBL12017402 | 0.72 | APP (0.49) | MEN1KMT2AAPPALDH1A1MAPT | |
| SCHEMBL20137819 | 0.72 | SRC (0.48) | KMT2AALDH1A1 | |
| SCHEMBL12844914 | 0.71 | MAOB (0.44) | KMT2AAPPALDH1A1MAPT | |
| SCHEMBL1243217 | 0.70 | RAB9A (0.47) | MEN1KMT2AAPPALDH1A1 | |
| SCHEMBL2021856 | 0.70 | AURKA (0.36) | MEN1KMT2AAPPALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139481-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-12-09 | — | — | WO | disclosed |