Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CPB1 | P15086 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28543689 | 0.89 | CPB1 (0.68) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL18077280 | 0.88 | ALDH1A1 (0.61) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL15420737 | 0.87 | CPB1 (0.56) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL15420736 | 0.87 | CPB1 (0.56) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL15420738 | 0.87 | CPB1 (0.56) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL16597461 | 0.86 | ALDH1A1 (0.55) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL19925393 | 0.86 | ALDH1A1 (0.55) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL10148184 | 0.85 | CPB1 (0.72) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL3063260 | 0.85 | CPB1 (0.72) | ALDH1A1GAACPB1TSHREPHX1 | |
| SCHEMBL579214 | 0.85 | CPB1 (0.72) | ALDH1A1GAACPB1TSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902400-B | Aromatic derivatives, process for their preparation and their medical use | 保仕健生物科技(上海)有限公司 | 2024-08-30 | — | — | CN | disclosed |
| EP-2694472-A2 | SULFONAMIDE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2014-02-12 | — | — | EP | disclosed |
| WO-2012137982-A9 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-14 | — | — | WO | disclosed |
| WO-2012137982-A2 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-10-11 | — | — | WO | disclosed |