SCHEMBL1024175

SCHEMBL1024175

O=C(N[C@@H](COCc1ccccc1)C(=O)O)OCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.64
FOLH1 Q04609 1/20 0.63
PPARG P37231 2/20 0.58
CTSK P43235 4/20 0.57
CTSL P07711 2/20 0.57
CTSS P25774 2/20 0.57
MME P08473 1/20 0.55
TACR1 P25103 2/20 0.54
CTRB1 P17538 2/20 0.54
CTSB P07858 1/20 0.53
IDO1 P14902 1/20 0.53
TDO2 P48775 1/20 0.53
CASP1 P29466 2/20 0.52
ALDH1A1 P00352 1/20 0.52
ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28595041 1.00 PPARA (0.64) PPARAFOLH1PPARGCTSKCTSL
SCHEMBL1171673 1.00 PPARA (0.64) PPARAFOLH1PPARGCTSKCTSL
SCHEMBL5827383 0.94 PPARA (0.62) PPARAFOLH1PPARGCTSKCTSL
SCHEMBL21837541 0.94 PPARA (0.58) PPARAFOLH1PPARGCTSKCTSL
SCHEMBL21837546 0.94 PPARA (0.58) PPARAFOLH1PPARGCTSKCTSL
SCHEMBL7319742 0.91 TACR1 (0.62) CTSKCTSLCTSSTACR1CTSB
SCHEMBL4391662 0.90 PPARA (0.57) PPARAFOLH1PPARGCTSKCTSL
SCHEMBL1170973 0.89 CTSK (0.56) PPARAFOLH1PPARGCTSKCTSL
SCHEMBL31456194 0.89 CTSK (0.60) PPARAFOLH1CTSKCTSLCTSS
SCHEMBL16351361 0.88 KYNU (0.62) PPARACTSKCTSLCTSSTACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US claimed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 US disclosed
WO-2025098391-A9 SELECTIVE DRUG RELEASE FROM CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS NONA BIOSCIENCES (SUZHOU) CO., LTD. (CN) 2026-04-30 WO disclosed
EP-3672582-B1 COMPOSITIONS AND METHODS FOR TREATING CANCER CEDARS SINAI MEDICAL CENTER (US) 2026-04-15 EP disclosed
US-20260015316-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER CEDARS-SINAI MEDICAL CENTER (US) 2026-01-15 US disclosed
US-12421185-B2 Compositions and methods for treating cancer CEDARS-SINAI MEDICAL CENTER (US) 2025-09-23 US disclosed
WO-2025098391-A1 SELECTIVE DRUG RELEASE FROM CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS NONA BIOSCIENCES (SUZHOU) CO., LTD. (CN) 2025-05-15 WO disclosed
CN-115053184-B Composition for forming EUV resist underlayer film 日产化学株式会社 2024-12-06 CN disclosed
CN-118619851-A Aminooxyacid-based antibacterial compounds and methods thereof 香港大学 2024-09-10 CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-4939241-A Diazo serines FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-07-03 US disclosed
WO-1990000399-A1 RETROVIRAL PROTEASE BINDING PEPTIDES SMITHKLINE BECKMAN CORPORATION (US) 1990-01-25 WO disclosed
EP-0352000-A2 Retroviral protease binding peptides SMITHKLINE BEECHAM CORPORATION (US) 1990-01-24 EP disclosed
EP-0285085-A2 Amino acid derivatives, process for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-10-05 EP disclosed
US-4668683-A Cardiotonic quinazoline derivatives KYOWA HAKKO KOGYO K.K. (JP) 1987-05-26 US disclosed
EP-0195667-A2 Cardiotonic quinazoline derivatives KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1986-09-24 EP disclosed
US-4564471-A N-/BENZYLOXYCARBONYL/ASPARTYLPHENYLALANINE AJINOMOTO CO., INC. (JP) 1986-01-14 US disclosed
EP-0027319-A2 Method for reductive elimination of protecting groups and preparative process using such method AJINOMOTO CO., INC. (JP) 1981-04-22 EP disclosed
US-4087520-A Lowering blood pressure with new L-3-(3,4-dihydroxyphenyl)-2-methyl-alanine peptides BOEHRINGER MANNHEIM GMBH (DT) 1978-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP PPARA 1878/4885FOLH1 4283/4885PPARG 853/4885
US-12421185-B2 Compositions and methods for treating cancer TSG101, RNASE1, TP53 PPARA 2140/4885FOLH1 25/4885PPARG 1746/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 PPARA 1752/4885FOLH1 3754/4885PPARG 2783/4885
US-20260015316-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER GLI1, RCC2, BRCA1 PPARA 3250/4885FOLH1 40/4885PPARG 1832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.