Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30674521 | 0.83 | ALDH1A1 (0.59) | DRD2DRD4CHRNB4CHRNA3ALDH1A1 | |
| SCHEMBL18404017 | 0.82 | CYP1A2 (0.59) | DRD2ALDH1A1ACHE | |
| SCHEMBL6318991 | 0.82 | KDM4E (0.49) | DRD2DRD4ADRA1AADRA1BACHE | |
| SCHEMBL6311181 | 0.82 | DRD2 (0.43) | DRD2DRD4CHRNB4CHRNA3KCNH2 | |
| SCHEMBL27599494 | 0.80 | HTR2C (0.51) | DRD2DRD4CHRNB4CHRNA3ALDH1A1 | |
| SCHEMBL1332177 | 0.80 | ABCB1 (0.60) | DRD2DRD4ADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL1475876 | 0.79 | HTR2C (0.53) | DRD2DRD4CHRNB4CHRNA3ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL4268987 | 0.79 | AVPR2 (0.50) | DRD2DRD4CHRNB4CHRNA3ALDH1A1 | |
| SCHEMBL11455709 | 0.78 | CHRNB4 (0.76) | CHRNB4CHRNA3ALDH1A1 | |
| SCHEMBL8689819 | 0.77 | ADRA1A (0.53) | KCNH2ALDH1A1ADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261218-A2 | Process for preparing phenyl-, pyridinyl- or pyrimidinyl-substituted imidazoles | Eisai R&D Management Co., Ltd. (JP) | 2010-12-15 | — | — | EP | disclosed |
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |