SCHEMBL12993265

SCHEMBL12993265

NCCOP(=O)(O)OCC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 1/20 0.38
MVD P53602 4/20 0.37
TSHR P16473 3/20 0.36
CTH P32929 2/20 0.36
CBS P35520 1/20 0.36
THPO P40225 1/20 0.36
THRB P10828 1/20 0.34
ITPR3 Q14573 1/20 0.33
ITPR1 Q14643 1/20 0.33
LMNA P02545 2/20 0.32
MEN1 O00255 1/20 0.31
HPGD P15428 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GLRA1 P23415 1/20 0.31
SLC6A9 P48067 1/20 0.31
OR51E2 Q9H255 1/20 0.31
P2RY10 O00398 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8852887 0.84 MVD (0.42) MVDTSHRCTHCBSTHPO
SCHEMBL11408483 0.84 PLA2G2C (0.41) PLA2G2CMVDTSHRTHPOITPR3
SCHEMBL14905894 0.82 BTN3A1 (0.35) PLA2G2CTSHRITPR3ITPR1ALDH1A1
SCHEMBL12374604 0.82 PLA2G2C (0.40) PLA2G2CMVDTSHRTHPOITPR3
SCHEMBL14878234 0.79 MVD (0.39) PLA2G2CMVDMEN1KMT2AALDH1A1
SCHEMBL16588370 0.76 BTN3A1 (0.34) PLA2G2CITPR3ITPR1
SCHEMBL369043 0.76 PLA2G2C (0.38) PLA2G2CTSHRITPR3ITPR1LMNA
SCHEMBL8768479 0.76 PLA2G2C (0.38) PLA2G2CTSHRTHPOITPR3ITPR1
SCHEMBL13498184 0.75 LPAR3 (0.55) P2RY10GPR34
SCHEMBL3135948 0.75 FABP3 (0.42) MVDTSHRLMNABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100304381-A1 FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS Life Technologies Corporation (US) 2010-12-02 US disclosed
US-7687236-B2 Fluorescent nucleobase conjugates having anionic linkers APPLIED BIOSYSTEMS, LLC (US) 2010-03-30 US disclosed
EP-1317464-B1 FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS APPLERA CORP (US) 2009-05-13 EP disclosed
US-20090092986-A1 Fluorescent Nucleobase Conjugates Having Anionic Linkers APPLIED BIOSYSTEMS INC. (US) 2009-04-09 US disclosed
US-7429651-B2 Fluorescent nucleobase conjugates having anionic linkers APPLERA CORPORATION (US) 2008-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100304381-A1 FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS DNTT, DUT, NT5C3B PLA2G2C 927/4885MVD 204/4885TSHR 3422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.