Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852351 | 0.86 | TDP1 (0.61) | TDP1GAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL13645618 | 0.81 | KMT2A (0.49) | TDP1RXFP1KMT2ASLC16A3MEN1 | |
| SCHEMBL4399333 | 0.80 | NPC1 (0.56) | TDP1GAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3863550 | 0.80 | SMN1; SMN2 (0.57) | TDP1SMN1; SMN2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8299753 | 0.78 | TDP1 (0.68) | TDP1GAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL29777391 | 0.77 | SMN1; SMN2 (0.68) | TDP1GAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL29777389 | 0.77 | SMN1; SMN2 (0.68) | TDP1GAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL975125 | 0.77 | SMN1; SMN2 (0.68) | TDP1GAASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL13645650 | 0.77 | SMN1; SMN2 (0.56) | GAASMN1; SMN2ALDH1A1HTTKDM4E | |
| SCHEMBL1367306 | 0.76 | TDP1 (0.65) | TDP1GAASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357816-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-01-22 | — | — | US | disclosed |
| US-20100305351-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-02 | — | — | US | disclosed |
| US-7767623-B2 | Siliconated phenyl amides derivatives useful as microbiocide | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305351-A1 | CHEMICAL COMPOUNDS | CYP2C9, CBR3, CBR1 | TDP1 4578/4885GAA 3340/4885SMN1; SMN2 4015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.