Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12995254 | 0.80 | TDP1 (0.55) | NPC1SMN1; SMN2HTTHPGDTDP1 | |
| SCHEMBL13292700 | 0.79 | PRNP (0.36) | NPC1SMN1; SMN2HTTHPGDALDH1A1 | |
| SCHEMBL12798767 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTKMT2AMEN1GAA | |
| SCHEMBL5577995 | 0.75 | ABCC1 (0.37) | NPC1SMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL8357735 | 0.74 | NPC1 (0.55) | NPC1SMN1; SMN2HTTHPGDTDP1 | |
| SCHEMBL12798733 | 0.74 | ATM (0.41) | NPC1SMN1; SMN2HTTHPGDALDH1A1 | |
| SCHEMBL8299753 | 0.73 | TDP1 (0.68) | NPC1SMN1; SMN2HTTHPGDTDP1 | |
| SCHEMBL12798730 | 0.70 | SMN1; SMN2 (0.34) | SMN1; SMN2HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL12798723 | 0.70 | LMNA (0.52) | ATMGAALMNA | |
| SCHEMBL7852351 | 0.70 | TDP1 (0.61) | NPC1SMN1; SMN2HTTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897780-B2 | Method for controlling phytopathogenic fungi using silylated carboxamides | BAYER CROPSCIENCE AG (DE) | 2011-03-01 | — | — | US | disclosed |
| US-7897780-B2 | Method for controlling phytopathogenic fungi using silylated carboxamides | BAYER CROPSCIENCE AG (DE) | 2011-03-01 | — | — | US | disclosed |
| EP-1727816-B1 | MICROBICIDAL SILYLATED CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1727816-B1 | MICROBICIDAL SILYLATED CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2009-12-30 | — | — | EP | disclosed |
| US-20070293455-A1 | Silylated Carboxamides | BAYER CROPSCIENCE AG (DE) | 2007-12-20 | — | — | US | disclosed |
| US-20070293455-A1 | Silylated Carboxamides | BAYER CROPSCIENCE AG (DE) | 2007-12-20 | — | — | US | disclosed |
| EP-1727816-A1 | SILYLATED CARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005095392-A1 | SILYLATED CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2005-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293455-A1 | Silylated Carboxamides | MRPL21, MRPS22, MRM1 | NPC1 3441/4885SMN1; SMN2 1838/4885HTT 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.