SCHEMBL975125

SCHEMBL975125

O=C(Nc1ccccc1Cl)c1cccnc1Cl

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.68
HPGD P15428 3/20 0.68
HTT P42858 2/20 0.68
CYP1A2 P05177 1/20 0.68
CYP2C19 P33261 1/20 0.68
TDP1 Q9NUW8 1/20 0.67
GAA P10253 2/20 0.64
KDR P35968 1/20 0.62
PABPC1 P11940 1/20 0.60
EIF4H Q15056 1/20 0.60
ALDH1A1 P00352 2/20 0.60
KDM4E B2RXH2 1/20 0.59
RXFP1 Q9HBX9 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
NPC1 O15118 3/20 0.57
MCL1 Q07820 1/20 0.56
GRM4 Q14833 1/20 0.54
KMT2A Q03164 2/20 0.54
RAB9A P51151 2/20 0.54
MEN1 O00255 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29777391 1.00 SMN1; SMN2 (0.68) SMN1; SMN2HPGDHTTCYP1A2CYP2C19
SCHEMBL29777389 1.00 SMN1; SMN2 (0.68) SMN1; SMN2HPGDHTTCYP1A2CYP2C19
SCHEMBL8299753 0.89 TDP1 (0.68) SMN1; SMN2HPGDHTTTDP1GAA
SCHEMBL9867402 0.88 KDR (0.70) SMN1; SMN2HPGDHTTCYP1A2CYP2C19
SCHEMBL28035894 0.86 TDP1 (0.65) SMN1; SMN2HPGDHTTTDP1GAA
SCHEMBL1367306 0.86 TDP1 (0.65) SMN1; SMN2HPGDHTTTDP1GAA
SCHEMBL971803 0.85 TDP1 (0.64) SMN1; SMN2HPGDHTTTDP1GAA
SCHEMBL4480002 0.85 CYP1A2 (0.64) SMN1; SMN2HPGDHTTCYP1A2CYP2C19
SCHEMBL9844353 0.84 TDP1 (0.63) SMN1; SMN2HPGDHTTTDP1GAA
SCHEMBL31680566 0.83 CYP1A2 (0.89) HPGDCYP1A2CYP2C19ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114878720-B Method for determining impurities in pesticide boscalid 江苏恒生检测有限公司 2024-03-15 CN claimed
CN-101952253-B Process for preparing substituted biphenylanilides BAYER CROPSCIENCE AG 2013-05-01 CN claimed
EP-2257530-B1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES BAYER CROPSCIENCE AG (DE) 2011-10-12 EP claimed
CN-101952253-A Process for preparing substituted biphenylanilides BAYER CROPSCIENCE AG 2011-01-19 CN claimed
US-20110003999-A1 Process for Preparing Substituted Biphenylanilides BAYER CROPSCIENCE AG (DE) 2011-01-06 US claimed
EP-2093216-A1 Process for preparing substituted biphenylanilides Bayer CropScience AG (DE) 2009-08-26 EP claimed
CN-114878720-B Method for determining impurities in pesticide boscalid 江苏恒生检测有限公司 2024-03-15 CN disclosed
CN-114878720-A Method for determining impurities in pesticide boscalid 江苏恒生检测有限公司 2022-08-09 CN disclosed
CN-105541709-A Method for preparing boscalid SHANG ZHENHUA 2016-05-04 CN disclosed
CN-101952253-B Process for preparing substituted biphenylanilides BAYER CROPSCIENCE AG 2013-05-01 CN disclosed
EP-2257530-B1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES BAYER CROPSCIENCE AG (DE) 2011-10-12 EP disclosed
CN-101952253-A Process for preparing substituted biphenylanilides BAYER CROPSCIENCE AG 2011-01-19 CN disclosed
US-20110003999-A1 Process for Preparing Substituted Biphenylanilides BAYER CROPSCIENCE AG (DE) 2011-01-06 US disclosed
EP-2093216-A1 Process for preparing substituted biphenylanilides Bayer CropScience AG (DE) 2009-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110003999-A1 Process for Preparing Substituted Biphenylanilides DDT, PAH, THOP1 SMN1; SMN2 3795/4885HPGD 1900/4885HTT 2937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.