Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28583230 | 0.98 | OPRM1 (0.44) | AKR1C1HDAC4GRIN2DGRIN3BCYP2B6 | |
| SCHEMBL1152247 | 0.98 | AKR1C1 (0.47) | AKR1C1HDAC4GRIN2DGRIN3BCYP2B6 | |
| Hydrochloric Acid SCHEMBL28579273 | 0.96 | AKR1C1 (0.45) | AKR1C1HDAC4GRIN2DGRIN3BCYP2B6 | |
| SCHEMBL1553 | 0.93 | AKR1C1 (0.42) | AKR1C1HDAC4OPRM1DPP4MEN1 | |
| Hydrochloric Acid SCHEMBL28589025 | 0.91 | AKR1C1 (0.41) | AKR1C1HDAC4OPRM1OPRD1DPP4 | |
| SCHEMBL568885 | 0.89 | MEN1 (0.41) | AKR1C1HDAC4OPRM1DPP4MEN1 | |
| SCHEMBL29002067 | 0.88 | SLC6A2 (0.50) | AKR1C1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL28581691 | 0.86 | MEN1 (0.40) | AKR1C1OPRM1OPRD1MEN1KMT2A | |
| SCHEMBL3885322 | 0.81 | MEN1 (0.36) | AKR1C1HDAC4OPRM1DPP4MEN1 | |
| SCHEMBL5197233 | 0.80 | AKR1C1 (0.40) | AKR1C1HDAC4GRIN2DGRIN3BCYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759587-B | 3- (dimethylamino methyl) piperidine-4-alcohol derivative and preparation method and pharmaceutical application thereof | 复旦大学 | 2022-12-30 | — | — | CN | claimed |
| CN-109369406-B | Photocatalytic synthesis method and application of 1-hydroxycyclohexyl phenyl ketone compound | 甘肃金盾化工有限责任公司 | 2021-12-14 | — | — | CN | claimed |
| CN-112759587-A | 3- (dimethylamino methyl) piperidine-4-alcohol derivative and preparation method and pharmaceutical application thereof | 复旦大学 | 2021-05-07 | — | — | CN | claimed |
| CN-109814336-A | Alkali soluble negative photosensitive polyimide resin combination | 深圳市道尔顿电子材料有限公司 | 2019-05-28 | — | — | CN | claimed |
| CN-109369406-A | A kind of photocatalytic synthesis method of 1- hydroxycyclohexyl phenyl ketone class compound and its application | 甘肃金盾化工有限责任公司 | 2019-02-22 | — | — | CN | claimed |
| CN-104293213-B | A kind of high tenacity low toxicity ultraviolet cured adhesive and preparation method thereof | CHENGDU NASHUO TECHNOLOGY CO., LTD. (CN) | 2016-04-20 | — | — | CN | claimed |
| CN-103282396-B | Aromatic hydrocarbon resin, composition for forming lithographic underlayer film, and method for forming multilayer resist pattern | MITSUBISHI GAS CHEMICAL CO | 2015-03-18 | — | — | CN | claimed |
| CN-104293213-A | High-ductility low-toxicity ultraviolet light polymerization glue and preparation method thereof | CHENGDU NASHUO TECHNOLOGY CO | 2015-01-21 | — | — | CN | claimed |
| CN-102574963-B | Aromatic hydrocarbon resin and underlayer film forming composition for lithography | MITSUBISHI GAS CHEMICAL CO | 2014-11-19 | — | — | CN | claimed |
| CN-103282396-A | Aromatic hydrocarbon resin, composition for forming lithographic underlayer film, and method for forming multilayer resist pattern | MITSUBISHI GAS CHEMICAL CO | 2013-09-04 | — | — | CN | claimed |
| CN-102827139-A | Liquid crystal monomer laterally-fluorinated cyclohexane-epoxyethane compound and synthesis method thereof | SHANDONG SHENGHUA ELECTRONIC NEW MATERIALS CO LTD | 2012-12-19 | — | — | CN | claimed |
| CN-102574963-A | Aromatic hydrocarbon resin and underlayer film forming composition for lithography | MITSUBISHI GAS CHEMICAL CO | 2012-07-11 | — | — | CN | claimed |
| US-20100179343-A1 | METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-07-15 | — | — | US | claimed |
| WO-2008121074-A1 | METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-10-09 | — | — | WO | claimed |
| EP-1311554-B1 | METHOD FOR PRODUCING ADHESIVE POLYACRYLATES USING MERCAPTO FUNCTIONAL PHOTOINITIATORS | TESA AG (DE) | 2004-11-03 | — | — | EP | claimed |
| US-20040049972-A1 | Method for producing adhesive polyacrylates using mercapto functional photoinitiators | TESA AG (DE) | 2004-03-18 | — | — | US | claimed |
| EP-1000047-B1 | 1-(N-PHENYLAMINOALKYL)-PIPERAZINE DERIVATIVES SUBSTITUTED AT POSITION 2 OF THE PHENYL RING | RECORDATI CHEM PHARM (CH) | 2003-12-17 | — | — | EP | claimed |
| JP-9143108-A | — | — | None | — | — | JP | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |
| US-4210602-A | REDUCTIVE ALKYLATION OF PARA-NITROSO-DIPHENYLHYDROXYLAMINE | AKZONA INCORPORATED (US) | 1980-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179343-A1 | METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE | TDO2, AOX1, DAO | AKR1C1 766/4885HDAC4 1548/4885GRIN2D 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.