Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12997240 | 0.95 | NQO1 (0.36) | APAF1L3MBTL1NQO1ALDH1A1LMNA | |
| SCHEMBL12997220 | 0.91 | CA1 (0.39) | APAF1L3MBTL1ALDH1A1MEN1NPC1 | |
| SCHEMBL12332660 | 0.86 | SMN1; SMN2 (0.36) | APAF1L3MBTL1KDM4ETDP2ALDH1A1 | |
| SCHEMBL1146949 | 0.84 | PABPC1 (0.34) | APAF1L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL1146947 | 0.84 | PABPC1 (0.34) | APAF1L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL13020967 | 0.84 | APAF1 (0.32) | APAF1L3MBTL1MEN1NPC1POLB | |
| SCHEMBL12997216 | 0.82 | DNM1 (0.37) | NQO1 | |
| SCHEMBL12332898 | 0.81 | BRCA1 (0.32) | APAF1L3MBTL1LMNAMAPK1 | |
| SCHEMBL12997296 | 0.81 | NQO1 (0.31) | NQO1 | |
| SCHEMBL13022286 | 0.80 | APAF1 (0.33) | APAF1L3MBTL1MEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142777-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM SECONDARY, N-ALKYLAMINATED PARA-PHENYLENEDIAMINES, METHOD OF HAIR DYEING USING THESE DYES | L'OREAL (FR) | 2010-12-16 | — | — | WO | disclosed |