SCHEMBL1299770

SCHEMBL1299770

CC(C)C1CCC(C=O)CC1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.30
ROCK1 Q13464 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10623586 1.00 ROCK2 (0.30) ROCK2ROCK1
SCHEMBL13190682 1.00 ROCK2 (0.30) ROCK2ROCK1
SCHEMBL7746232 0.93
SCHEMBL21591990 0.80 ROCK2 (0.33) ROCK2ROCK1
SCHEMBL887223 0.80
SCHEMBL18560523 0.80 ROCK2 (0.33) ROCK2ROCK1
SCHEMBL28772429 0.78
SCHEMBL887222 0.76 ADH1A (0.32)
SCHEMBL22462729 0.76 NOS3 (0.33) ROCK2ROCK1
SCHEMBL8677451 0.76 NOS3 (0.33) ROCK2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2806031-A2 Method for searching for malodor control agent, malodor control agent, and malodor control method Kao Corporation (JP) 2014-11-26 EP claimed
US-20130216492-A1 Method for Searching for Malodor Control Agent, Malodor Control Agent, and Malodor Control Method KAO CORPORATION (JP) 2013-08-22 US claimed
EP-2612923-A1 METHOD FOR SEARCHING FOR MALODOR CONTROL AGENT, MALODOR CONTROL AGENT, AND MALODOR CONTROL METHOD Kao Corporation (JP) 2013-07-10 EP claimed
US-12612380-B2 Non-lysosomal glucosylceramidase inhibitors and uses thereof ALECTOS THERAPEUTICS 1NC (CA) 2026-04-28 US disclosed
EP-3966199-B1 NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF ALECTOS THERAPEUTICS INC (CA) 2026-03-18 EP disclosed
CN-114174263-B Non-lysosomal glucosylceramidase inhibitors and uses thereof 阿勒克图治疗公司 2025-01-10 CN disclosed
US-20240059658-A1 QUINOLINE DERIVATIVES AND USES IN MANAGING CANCER UNIV EMORY (US) 2024-02-22 US disclosed
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
US-20220402965-A1 STEROL ANALOGS AND USES THEREOF ARES CAPITAL CORPORATION, AS AGENT 2022-12-22 US disclosed
US-20220213058-A1 NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF ALECTOS THERAPEUTICS INC. (CA) 2022-07-07 US disclosed
EP-3966199-A1 NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF Alectos Therapeutics Inc. (CA) 2022-03-16 EP disclosed
WO-1999037611-A1 HETEROCYCLIC AMIDINES AS CALLICREIN PROTEASE INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1999-07-29 WO disclosed
WO-1999037668-A1 THROMBIN INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1999-07-29 WO disclosed
EP-0918792-A1 DIPEPTIDE BENZAMIDINE AS A KININOGENASE INHIBITOR BASF AKTIENGESELLSCHAFT (DE) 1999-06-02 EP disclosed
WO-1998006741-A1 THROMBIN INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1998-02-19 WO disclosed
WO-1998006740-A1 DIPEPTIDE BENZAMIDINE AS A KININOGENASE INHIBITOR BASF AKTIENGESELLSCHAFT (DE) 1998-02-19 WO disclosed
US-4786332-A TOBACCO PRODUCTS GIVAUDAN CORPORATION (US) 1988-11-22 US disclosed
EP-0110362-B1 FRAGRANCE AND FLAVOUR COMPOSITIONS L. GIVAUDAN & CIE Société Anonyme (CH) 1988-04-20 EP disclosed
US-4606925-A Flavoring with alkyl-substituted cyclohexyl and cyclohexenyl carboxylic acids GIVAUDAN CORPORATION (US) 1986-08-19 US disclosed
EP-0110362-A2 Fragrance and flavour compositions L. GIVAUDAN & CIE Société Anonyme (CH) 1984-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130216492-A1 Method for Searching for Malodor Control Agent, Malodor Control Agent, and Malodor Control Method OR51E2, OR10J3, ORMDL3 ROCK2 2577/4885ROCK1 3057/4885
US-20240059658-A1 QUINOLINE DERIVATIVES AND USES IN MANAGING CANCER MDM2, TP53, RECQL ROCK2 2544/4885ROCK1 3180/4885
US-20220213058-A1 NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF GBA1, GBA2, GAA ROCK2 4004/4885ROCK1 4002/4885
US-12612380-B2 Non-lysosomal glucosylceramidase inhibitors and uses thereof GBA1, GBA2, MAN2B1 ROCK2 2586/4885ROCK1 2665/4885
US-20220402965-A1 STEROL ANALOGS AND USES THEREOF NPC1L1, NPC1, SREBF2 ROCK2 2285/4885ROCK1 1938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.