Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 2/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12998270 | 0.86 | ALDH1A1 (0.48) | NLRP3ALDH1A1SMN1; SMN2LMNAHPGD | |
| Efaproxiral SCHEMBL1649963 | 0.86 | PPARA (0.54) | PPARACYP1A2CYP3A4NLRP3ALDH1A1 | |
| Efaproxiral SCHEMBL3768310 | 0.85 | PPARA (0.52) | PPARACYP1A2CYP3A4RORCNLRP3 | |
| SCHEMBL14341054 | 0.85 | ALDH1A1 (0.51) | NLRP3ALDH1A1SMN1; SMN2LMNAHPGD | |
| Efaproxiral SCHEMBL3763811 | 0.84 | ALDH1A1 (0.49) | NLRP3ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL16861099 | 0.84 | MEN1 (0.42) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL16861085 | 0.82 | MAPK1 (0.41) | RORCNLRP3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6353457 | 0.81 | ALDH1A1 (0.45) | PPARARORCNLRP3ALDH1A1SMN1; SMN2 | |
| SCHEMBL6357176 | 0.81 | ALDH1A1 (0.44) | PPARANLRP3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6357197 | 0.79 | PPARA (0.51) | PPARAABCB11CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7847120-B2 | Compositions of allosteric hemoglobin modifiers and methods of making the same | VIRGINIA COMMONWEALTH UNIVERSITY INTELLECTUAL PROPERTY FOUNDATION (US) | 2010-12-07 | — | — | US | disclosed |
| US-7847120-B2 | Compositions of allosteric hemoglobin modifiers and methods of making the same | VIRGINIA COMMONWEALTH UNIVERSITY INTELLECTUAL PROPERTY FOUNDATION (US) | 2010-12-07 | — | — | US | disclosed |
| US-20070293698-A1 | Compositions of Allosteric Hemoglobin Modifiers and Methods of Making the Same | ALLOS THERAPEUTICS, INC. (US) | 2007-12-20 | — | — | US | disclosed |
| US-20070293698-A1 | Compositions of Allosteric Hemoglobin Modifiers and Methods of Making the Same | ALLOS THERAPEUTICS, INC. (US) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293698-A1 | Compositions of Allosteric Hemoglobin Modifiers and Methods of Making the Same | HBB, HBZ, HBG2 | PPARA 1401/4885ABCB11 4807/4885CYP1A2 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.