SCHEMBL1300141

SCHEMBL1300141

CCOC(=O)C(=O)CCCC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.53
SLC22A6 Q4U2R8 2/20 0.48
KYAT1 Q16773 4/20 0.45
TSHR P16473 4/20 0.45
AKR1B1 P15121 1/20 0.44
EGLN1 Q9GZT9 1/20 0.44
PPARG P37231 5/20 0.43
PPARD Q03181 5/20 0.43
PPARA Q07869 5/20 0.43
HDAC11 Q96DB2 4/20 0.43
GPR84 Q9NQS5 3/20 0.43
ALDH1A1 P00352 2/20 0.43
TLR2 O60603 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
FABP4 P15090 2/20 0.43
PTPN1 P18031 2/20 0.43
SLC22A8 Q8TCC7 1/20 0.43
MEN1 O00255 1/20 0.43
ESR1 P03372 1/20 0.43
ALOX15 P16050 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11484529 0.96 FAAH (0.58) FAAHSLC22A6TSHRAKR1B1PPARG
SCHEMBL18101453 0.91 FAAH (0.60) FAAHTSHREGLN1ALDH1A1ALOX15
SCHEMBL118022 0.86 FAAH (0.47) FAAHTSHREGLN1ALDH1A1MEN1
SCHEMBL10704882 0.84 FAAH (0.69) FAAHTSHRALDH1A1ALOX15HSD17B10
SCHEMBL15842189 0.83 CYP1A2 (0.57) FAAHTSHRALDH1A1TDP1ALOX15
SCHEMBL910019 0.82 FAAH (0.67) FAAHALDH1A1HSD17B10
SCHEMBL29747328 0.82 AKR1B1 (0.50) FAAHSLC22A6TSHRAKR1B1PPARG
SCHEMBL16046274 0.81 FAAH (0.53) FAAHTSHREGLN1ALDH1A1MEN1
SCHEMBL3014656 0.80 FAAH (0.76) FAAHSLC22A6TSHRAKR1B1PPARG
SCHEMBL7330520 0.79 SLC22A6 (0.44) SLC22A6KYAT1TSHRAKR1B1EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115667244-B 3-azabicycloalkyl derivatives and pharmaceutical compositions containing the same 株式会社LG化学 2024-04-12 CN disclosed
US-20230203008-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME LG CHEM, LTD. (KR) 2023-06-29 US disclosed
US-20230203008-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME LG CHEM, LTD. (KR) 2023-06-29 US disclosed
US-20230203008-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME LG CHEM, LTD. (KR) 2023-06-29 US disclosed
EP-4134366-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Lg Chem, Ltd. (KR) 2023-02-15 EP disclosed
CN-115667244-A 3-azabicycloalkyl derivatives and pharmaceutical compositions comprising the same 株式会社LG化学 2023-01-31 CN disclosed
WO-2021215765-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 주식회사 엘지화학 (KR) 2021-10-28 WO disclosed
US-9023636-B2 Microorganisms and methods for the biosynthesis of propylene GENOMATICA, INC. (US) 2015-05-05 US disclosed
US-8617862-B2 Microorganisms for producing propylene and methods related thereto GENOMATICA, INC. (US) 2013-12-31 US disclosed
EP-2563926-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE Genomatica, Inc. (US) 2013-03-06 EP disclosed
US-20120329119-A1 MICROORGANISMS FOR PRODUCING PROPYLENE AND METHODS RELATED THERETO GENOMATICA, INC. 2012-12-27 US disclosed
WO-2011137198-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE GENOMATICA, INC. (US) 2011-11-03 WO disclosed
US-20110269204-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE AGAIN BIO APS (DK) 2011-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203008-A1 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ADCY1, ADCY7 FAAH 623/4885SLC22A6 1111/4885KYAT1 1745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.