SCHEMBL118022

SCHEMBL118022

CCOC(=O)C(=O)CCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.47
EGLN1 Q9GZT9 3/20 0.47
MAPK1 P28482 1/20 0.46
SLC13A3 Q8WWT9 1/20 0.46
OR51E2 Q9H255 1/20 0.46
ALDH1A1 P00352 5/20 0.44
CYP2D6 P10635 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
LMNA P02545 3/20 0.43
ALKBH5 Q6P6C2 1/20 0.43
SUCNR1 Q9BXA5 1/20 0.43
FFAR3 O14843 1/20 0.42
HDAC3 O15379 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
SLC15A2 Q16348 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GLO1 Q04760 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16046274 0.90 FAAH (0.53) FAAHEGLN1ALDH1A1CYP2D6SMN1; SMN2
SCHEMBL11484529 0.86 FAAH (0.58) FAAHOR51E2ALDH1A1LMNAHSD17B10
SCHEMBL1300141 0.86 FAAH (0.53) FAAHEGLN1OR51E2ALDH1A1HSD17B10
SCHEMBL16046412 0.86 FAAH (0.47) FAAHEGLN1MAPK1SLC13A3OR51E2
SCHEMBL4445881 0.82 FFAR3 (0.44) EGLN1MAPK1SLC13A3OR51E2ALDH1A1
Alpha-Ketoglutaric Acid SCHEMBL30292150 0.81 EGLN1 (0.48) FAAHEGLN1MAPK1SLC13A3OR51E2
SCHEMBL3533002 0.81 GAA (0.50) FAAHALDH1A1SMN1; SMN2LMNAHSD17B10
SCHEMBL2402800 0.80 EGLN1 (0.50) EGLN1MAPK1SLC13A3OR51E2ALDH1A1
SCHEMBL18101453 0.80 FAAH (0.60) FAAHEGLN1ALDH1A1LMNAHSD17B10
SCHEMBL112407 0.80 CES2 (0.55) FAAHEGLN1ALDH1A1LMNAFFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2555803-B1 PROCESS FOR PREPARING HYPERPOLARIZED SUBSTRATES AND METHOD FOR MRI BRACCO IMAGING SPA (IT) 2018-09-12 EP claimed
US-9694090-B2 Process for preparing hyperpolarized substrates and method for MRI BRACCO IMAGING S.P.A. (IT) 2017-07-04 US claimed
US-20130096420-A1 Process For Preparing Hyperpolarized Substrates And Method For MRI BRACCO IMAGING S.P.A. (IT) 2013-04-18 US claimed
EP-2555803-A1 PROCESS FOR PREPARING HYPERPOLARIZED SUBSTRATES AND METHOD FOR MRI Bracco Imaging S.p.A (IT) 2013-02-13 EP claimed
WO-2011124672-A1 PROCESS FOR PREPARING HYPERPOLARIZED SUBSTRATES AND METHOD FOR MRI BRACCO IMAGING SPA (IT) 2011-10-13 WO claimed
US-20090048153-A1 COMPOSITION FOR TREATING SULFUR MUSTARD TOXICITY AND METHODS OF USING SAME UNIVERSITY OF MARYLAND, BALTIMORE (US) 2009-02-19 US claimed
US-20030181506-A1 Selective preventives/remedies for progressive lesions after organ damage ISHIBASHI, MICHIO (JP) 2003-09-25 US claimed
EP-1277747-A1 SELECTIVE PREVENTIVES/REMEDIES FOR PROGRESSIVE LESIONS AFTER ORGAN DAMAGE Ishibashi, Michio (JP) 2003-01-22 EP claimed
EP-4735906-A1 SYSTEMS AND METHODS FOR HYPERPOLARIZED NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND MAGNETIC RESONANCE IMAGING NVision Imaging Technologies GmbH (DE) 2026-05-06 EP disclosed
EP-4587413-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS NVision Imaging Technologies GmbH (DE) 2025-07-23 EP disclosed
EP-4587850-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS NVision Imaging Technologies GmbH (DE) 2025-07-23 EP disclosed
US-20250091980-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS NVISION IMAGING TECHNOLOGIES GMBH (DE) 2025-03-20 US disclosed
CN-119587524-A Application of alpha ketoglutarate prodrug in preparation of medicines for treating myelodysplastic syndrome 浙江大学 2025-03-11 CN disclosed
WO-2025003849-A1 SYSTEMS AND METHODS FOR HYPERPOLARIZED NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND MAGNETIC RESONANCE IMAGING NVISION IMAGING TECHNOLOGIES GMBH (DE) 2025-01-02 WO disclosed
CN-1293674-A Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient TORAY INDUSTRIES (JP) 2001-05-02 CN disclosed
WO-2000053313-A2 LANTHANIDE CATALYSTS FOR SYNTHESIS OF COMPOUNDS AND COMBINATORIAL LIBRARIES ARQULE, INC. (US) 2000-09-14 WO disclosed
US-4876251-A ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-10-24 US disclosed
EP-0249909-A1 Tricyclic penam compounds, their production and their use Takeda Chemical Industries, Ltd. (JP) 1987-12-23 EP disclosed
EP-0056489-B1 A CONTINUOUS PROCESS FOR THE PREPARATION OF ADIPIC ACID BASF Aktiengesellschaft (DE) 1984-08-22 EP disclosed
EP-0056489-A1 A continuous process for the preparation of adipic acid BASF Aktiengesellschaft (DE) 1982-07-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090048153-A1 COMPOSITION FOR TREATING SULFUR MUSTARD TOXICITY AND METHODS OF USING SAME TST, SQOR, QSOX1 FAAH 1021/4885EGLN1 739/4885MAPK1 2105/4885
US-20030181506-A1 Selective preventives/remedies for progressive lesions after organ damage CCL11, CD68, CCL2 FAAH 2777/4885EGLN1 4294/4885MAPK1 2510/4885
US-20130096420-A1 Process For Preparing Hyperpolarized Substrates And Method For MRI HOGA1, HAMP, GLS2 FAAH 768/4885EGLN1 38/4885MAPK1 1116/4885
US-20250091980-A1 SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS GLS2, HNMT, FH FAAH 2469/4885EGLN1 422/4885MAPK1 3965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.